The Potential Teratogenicity Alert for Women Conceiving on Dolutegravir‑Based Regimens: An Assessment of Risk Communication by an Urban HIV Clinic in Uganda and Choices made by Women

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dc.contributor.authorLaker, Eva Agnes Odongpiny
dc.contributor.authorArinaitwe, Arnold
dc.contributor.authorOwarwo, Noela
dc.contributor.authorOnzia, Annet
dc.contributor.authorNasasira, Benson
dc.contributor.authorWailagala, Abdullah
dc.contributor.authorKalule, Ivan
dc.contributor.authorAnguzu, Godwin
dc.contributor.authorKiragga, Agnes
dc.contributor.authorLwanga, Isaac
dc.contributor.authorCastelnuovo, Barbara
dc.contributor.authorMusomba, Rachel
dc.contributor.authorLamorde, Mohammed
dc.date.accessioned2023-05-30T16:48:32Z
dc.date.available2023-05-30T16:48:32Z
dc.date.issued2020
dc.description.abstractIn May 2018, the World Health Organization and other regulatory authorities released a safety alert for dolutegravir related to a risk of neural tube defects among women exposed to dolutegravir at the time of conception. Models of how drug safety information can be shared effectively in the shortest time are necessary to prevent interruptions of public health programs. We sought to describe an implementation process to inform and support women already on dolutegravir-based regimens at the time of conception to make informed choices following the safety alert of a potential teratogenicity risk. We describe the choices made by women, as well as determine the factors associated with women’s choices to switch off dolutegravir.en_US
dc.identifier.citationLaker, E. A. O., Arinaitwe, A., Owarwo, N., Onzia, A., Nasasira, B., Wailagala, A., ... & Lamorde, M. (2020). The potential teratogenicity alert for women conceiving on dolutegravir-based regimens: an assessment of risk communication by an urban HIV clinic in Uganda and choices made by women. Drug Safety, 43, 1133-1140.https://doi.org/10.1007/s40264-020-00974-9en_US
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8841
dc.language.isoenen_US
dc.publisherDrug Safetyen_US
dc.subjectWomenen_US
dc.subjectUrban HIV Clinicen_US
dc.subjectDolutegravir-Based Regimensen_US
dc.subjectConceptionen_US
dc.titleThe Potential Teratogenicity Alert for Women Conceiving on Dolutegravir‑Based Regimens: An Assessment of Risk Communication by an Urban HIV Clinic in Uganda and Choices made by Womenen_US
dc.typeArticleen_US
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