Malariological baseline survey and in vitro antimalarial drug resistance in Gulu district, Northern Uganda

A comprehensive, representative malaria survey has been carried out in a population of internally displaced persons (IDP) in the district of Gulu, Northern Uganda. It included 74 households and 390 persons, and covered socio-economic and environmental information, individual physical data, malaria and the drug sensitivity of Plasmodium falciparum. The prevalence of infections with Plasmodium falciparum was 54.4% at a geometric mean asexual parasitaemia of 229/μl blood, typical for hyperendemic conditions. P. falciparum turned out to be highly resistant to chloroquine and amodiaquine. It showed also reduced sensitivity against lumefantrine and artemisinin, obviously the result of the liberal use of the lumefantrine-artemether combination without evidence-based indication.

Keywords

Malaria, Prevalence, Plasmodium falciparum, Drug sensitivity, Uganda

Citation

Prugger, C., Engl, M., Ogwang, M., Ploner, F., Ploner, M., Gluderer, D., ... & Wernsdorfer, W. H. (2008). Malariological baseline survey and in vitro antimalarial drug resistance in Gulu district, Northern Uganda. Wiener klinische Wochenschrift, 120(4), 63-68. DOI 10.1007/s00508-008-1037-y

URI

https://nru.uncst.go.ug/handle/123456789/2985

Collections

Medical and Health Sciences

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