Helicobacter pylori among patients with symptoms of gastroduodenal ulcer disease in rural Uganda

Simple item page
dc.contributor.authorTsongo, Lawrence
dc.contributor.authorNakavuma, Jessica
dc.contributor.authorMugasa, Claire
dc.contributor.authorKamalha, Edwin
dc.date.accessioned2022-12-04T13:14:40Z
dc.date.available2022-12-04T13:14:40Z
dc.date.issued2015
dc.description.abstractTo meet key millennium development goals, the rural population needs to be reached for health assessment and service delivery. Gastroduodenal ulcer disease is a common ailment affecting the health of people in Uganda. A cross-sectional study was conducted at Bwera Hospital in Kasese district of western Uganda, to establish the prevalence and predisposing factors of Helicobacter pylori among gastroduodenal ulcer disease patients. Methods: A sample of 174 patients with symptoms of gastroduodenal ulcer disease was purposively obtained. Using two laboratory test methods, the prevalence of H. pylori among these patients was determined. A structured questionnaire was administered to participants to establish their demographic background and selected aspects of their lifestyle. Finally, the results obtained by enzyme-linked immunosorbent assay (ELISA) and immunochromatographic rapid test (IRT) were compared. Results: We established the prevalence of H. pylori as 29.9% (52/174) by ELISA and 37.4% (65/174) by IRT. Cigarette smoking, poor sanitation, and lack of formal education were the significant predisposing factors with p-values B0.05. The two tests gave identical results in 87.9% of the patients. Discussion: The prevalence of H. pylori by IRT and ELISA test methods was similar to what has been reported elsewhere in developed countries; but was lower than previously reported in developing countries including Uganda. The previous studies in Uganda were carried out in the urban population and on young children; and some used antibody-detection methods only, therefore leading to different prevalence as a result of difference in study population and methods.en_US
dc.identifier.citationLawrence Tsongo, Jessica Nakavuma, Claire Mugasa & Edwin Kamalha (2015) Helicobacter￿pylori among patients with symptoms of gastroduodenal ulcer disease in rural Uganda, Infection Ecology & Epidemiology, 5:1, 26785, DOI: 10.3402/iee.v5.26785en_US
dc.identifier.urihttps://doi.org/10.3402/iee.v5.26785
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/5827
dc.language.isoenen_US
dc.publisherInfection Ecology & Epidemiologyen_US
dc.subjectHelicobacter pylorien_US
dc.subjectPeptic ulcersen_US
dc.subjectSymptomsen_US
dc.subjectGastroduodenal ulceren_US
dc.subjectChronic gastritisen_US
dc.subjectSmokingen_US
dc.titleHelicobacter pylori among patients with symptoms of gastroduodenal ulcer disease in rural Ugandaen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Helicobacter pylori among patients with symptoms.pdf
Size:
692.52 KB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medical and Health Sciences