Genital infections and risk of premature rupture of membranes in Mulago Hospital, Uganda: a case control study

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dc.contributor.authorNakubulwa, Sarah
dc.contributor.authorKaye, Dan K.
dc.contributor.authorBwanga, Freddie
dc.contributor.authorMbona Tumwesigye, Nazarius
dc.contributor.authorMirembe, Florence M.
dc.date.accessioned2022-01-21T18:50:44Z
dc.date.available2022-01-21T18:50:44Z
dc.date.issued2015
dc.description.abstractInflammatory mediators that weaken and cause membrane rupture are released during the course of genital infections among pregnant women. We set out to determine the association of common genital infections (Trichomonas vaginalis, syphilis, Neisseria gonorrhea, Chlamydia trachomatis, Group B Streptococcus, Bacterial vaginosis, Herpes Simplex Virus Type 2 and candidiasis) and premature rupture of membranes in Mulago hospital, Uganda. Methods: We conducted an unmatched case–control study among women who were in the third trimester of pregnancy at New Mulago hospital, Uganda. The cases had PROM and the controls had intact membranes during latent phase of labour in the labour ward. We used interviewer-administered questionnaires to collect data on sociodemographic characteristics, obstetric and medical history. Laboratory tests were conducted to identify T. vaginalis, syphilis, N. gonorrhea, C. trachomatis, Group B Streptococcus, Bacterial vaginosis, Herpes Simplex Virus Type 2 (HSV-2) and candidiasis. Logistic regression models were used to estimate the odds ratios (OR) and 95 % CI of the association between genital infections and PROM.en_US
dc.identifier.citationNakubulwa, S., Kaye, D. K., Bwanga, F., Tumwesigye, N. M., & Mirembe, F. M. (2015). Genital infections and risk of premature rupture of membranes in Mulago Hospital, Uganda: a case control study. BMC research notes, 8(1), 1-9. DOI 10.1186/s13104-015-1545-6en_US
dc.identifier.other10.1186/s13104-015-1545-6
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1391
dc.language.isoenen_US
dc.publisherBMC research notesen_US
dc.subjectGenital infectionsen_US
dc.subjectPremature rupture of membranes (PROM)en_US
dc.subjectRisken_US
dc.subjectUgandaen_US
dc.titleGenital infections and risk of premature rupture of membranes in Mulago Hospital, Uganda: a case control studyen_US
dc.typeArticleen_US
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