A serological survey for antibodies against foot-and-mouth disease virus (FMDV) in domestic pigs during outbreaks in Kenya

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dc.contributor.authorWekesa, Sabenzia N.
dc.contributor.authorSangula, Abraham K.
dc.contributor.authorMuwanika, Vincent B.
dc.contributor.authorNamatovu, Alice
dc.contributor.authorDhikusooka, Moses T.
dc.contributor.authorTjørnehøj, Kirsten
dc.date.accessioned2022-05-26T11:01:53Z
dc.date.available2022-05-26T11:01:53Z
dc.date.issued2014
dc.description.abstractFoot-and-mouth disease (FMD) is endemic in Kenya and has been well studied in cattle, but not in pigs, yet the role of pigs is recognised in FMD-free areas. This study investigated the presence of antibodies against FMD virus (FMDV) in pigs sampled during a countrywide random survey for FMD in cattle coinciding with SAT 1 FMDV outbreaks in cattle. A total of 191 serum samples were collected from clinically healthy pigs in 17 districts. Forty-two of the 191 sera were from pigs vaccinated against serotypes O/A/ SAT 2 FMDV. Antibodies against FMDV non-structural proteins were found in sera from 30 vaccinated and 71 nonvaccinated pigs, altogether 101/191 sera (53 %), and 91 % of these (92/101) also had antibodies measurable by serotypespecific ELISAs, predominantly directed against SAT 1 with titres of 10–320. However, only five high titres against SAT 1 in vaccinated pigs were confirmed by virus neutralisation test (VNT). Due to high degree of agreement between the two ELISAs, it was concluded that positive pigs had been infected with FMDV. Implications of these results for the role of pigs in the epidemiology of FMD in Kenya are discussed, and indepth studies are recommended.en_US
dc.identifier.citationWekesa, S. N., Namatovu, A., Sangula, A. K., Dhikusooka, M. T., Muwanika, V. B., & Tjørnehøj, K. (2014). A serological survey for antibodies against foot-and-mouth disease virus (FMDV) in domestic pigs during outbreaks in Kenya. Tropical animal health and production, 46(3), 575-581.DOI 10.1007/s11250-013-0530-0en_US
dc.identifier.otherDOI 10.1007/s11250-013-0530-0
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/3453
dc.language.isoenen_US
dc.publisherTropical animal health and productionen_US
dc.subjectDomestic pigsen_US
dc.subjectEastern Africaen_US
dc.subjectEndemic areasen_US
dc.subjectFoot-and-mouth diseaseen_US
dc.titleA serological survey for antibodies against foot-and-mouth disease virus (FMDV) in domestic pigs during outbreaks in Kenyaen_US
dc.typeArticleen_US
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