Effects of Medical Male Circumcision (MC) on Plasma HIV Viral Load in HIV+ HAART Nai¨ve Men; Rakai, Uganda

Abstract
Medical male circumcision (MC) of HIV-infected men may increase plasma HIV viral load and place female partners at risk of infection. We assessed the effect of MC on plasma HIV viral load in HIV-infected men in Rakai, Uganda. 195 consenting HIV-positive, HAART naı¨ve men aged 12 and above provided blood for plasma HIV viral load testing before surgery and weekly for six weeks and at 2 and 3 months post surgery. Data were also collected on baseline social demographic characteristics and CD4 counts. Change in log10 plasma viral load between baseline and follow-up visits was estimated using paired t tests and multivariate generalized estimating equation (GEE).
Description
Keywords
Medical Male Circumcision (MC), Plasma HIV Viral Load, HIV+ HAART, Uganda
Citation
Kigozi G, Musoke R, Kighoma N, Watya S, Serwadda D, et al. (2014) Effects of Medical Male Circumcision (MC) on Plasma HIV Viral Load in HIV+ HAART Naı¨ve Men; Rakai, Uganda. PLoS ONE 9(11): e110382. doi:10.1371/journal.pone. 0110382