GC-MS Analysis of Bioactive Phytochemicals Present in Ethanolic Extracts of Leaves of Annona muricata: A Further Evidence for Its Medicinal Diversity
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Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Pharmacognosy Journal
Abstract
Folk medicine has taken an important place especially in developing
countries where limited health services are available. However,
the absence of scientific evaluation of medicinal plants may cause serious
adverse effects. Objective: To analyze the phytochemical composition of
the ethanolic extracts of leaves of Annona muricata using gas chromatography
mass spectroscopy (GC-MS). Materials and methods: GC-MS Analysis
was used. Results: The GC-MS Analysis revealed 25 constituents of
which 12 of the compounds were identified. The major constituents were
two unidentified compounds with percentage peak areas of 23.51% and
16.8%. Of the identified compounds, the outstanding in composition were
7-Tetradecenal, (Z) (peak area 9.39%), n-Hexadecanoic acid (peak area
7.12%), Oleyl Alcohol (peak area 6.15%), Phytol (peak area 5.61%), cis,
cis, cis-7,10,13-Hexadecatrienal (peak area 4.26%), 2-Pentadecanol (peak
area 3.93%), 9,12-Octadecadienoic acid, ethyl ester (peak area 3.21%),
1,2-Benzenedicarboxylic acid, butyl octyl ester (peak area 2.67%), and 1,E-
11,Z-13-Octadecatriene (peak area 2.15%), while the rest had less than 2%
composition by peak area. Conclusion: The current study suggests that
ethanolic extracts of leaves of Annona muricata are a potent therapeutic
agent and paves the way for the development of several treatment regimens
based on compounds from this extract.
Description
Keywords
Annona muricata, Ethanolic extracts, GC-MS, Medicinal diversity, Phytochemicals
Citation
Gavamukulya, Y., Abou-Elella, F., Wamunyokoli, F., & El-Shemy, H. A. (2015). GC-MS analysis of bioactive phytochemicals present in ethanolic extracts of leaves of Annona muricata: A further evidence for its medicinal diversity. Pharmacognosy Journal, 7(5). DOI : 10.5530/pj.2015.5.9