Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
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Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Medical mycology case reports
Abstract
The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking pre-
sentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryp-
tococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meningitis
who presented with subacute, worsening abdominal pain during immune recovery. This evolved into
chronic abdominal pain, with thickened bowel, and abdominal lymphadenopathy, while receiving em-
piric tuberculosis treatment. At 6-months, he developed intestinal perforation due to a histologically
confirmed cryptococcoma.
Description
Keywords
HIV, AIDS, Cryptococcal meningitis, Cryptococcoma, Antiretroviral therapy, Immune reconstitution inflammatory, Syndrome
Citation
Musubire, A. K., Meya, D. B., Lukande, R., Kambugu, A., Bohjanen, P. R., & Boulware, D. R. (2015). Gastrointestinal cryptococcoma–Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?. Medical mycology case reports, 8, 40-43.