Functioning and activity outcomes of the Akwenda Intervention Program for children and young adults with cerebral palsy in Uganda: A cluster-randomized trial

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dc.contributor.authorAsige, Elizabeth
dc.contributor.authorSaloojee, Gillian
dc.contributor.authorAndrews, Carin
dc.contributor.authorNamaganda, Lukia H
dc.contributor.authorKakooza‐Mwesige, Angelina
dc.contributor.authorDamiano, Diane L
dc.contributor.authorForssberg, Hans
dc.date.accessioned2025-01-09T12:16:53Z
dc.date.available2025-01-09T12:16:53Z
dc.date.issued2025-01
dc.description.abstractAim To evaluate the efficacy of the Akwenda Intervention Program on motor, self-care, and social function of children and young people with cerebral palsy (CP). Method This was a cluster-randomized, controlled, single-blinded, intervention study of 100 participants with CP (2–23 years; 52 males) in rural eastern Uganda. Half were allocated to the intervention program, the remainder served as waitlist controls. Gross Motor Function Measure-66 (GMFM-66) and the Ugandan version of Pediatric Evaluation of Disability Inventory (PEDI-UG) were collected before group allocation and after intervention. General linear models and t -tests were used to compare changes within and between groups. Cohen's d estimated the effect size of group differences. Change scores were evaluated by age and mobility subgroups. Results Significant group by time interactions were found for GMFM-66 ( p  =0.003) and PEDI-UG outcomes ( p  <0.001), except mobility, with the intervention group demonstrating greater changes. Both groups increased their scores on the GMFM-66 and child PEDI-UG, while only the intervention group had significant increases in caregiver assistance scores and across all age and mobility subgroups. Cohen's d showed large effect sizes ( d  >0.8) of differences for PEDI-UG outcomes except mobility. Interpretation The Akwenda Intervention Program had a large positive impact on functioning and activity across age and mobility levels.
dc.description.sponsorshipVetenskapsrådet, Grant/Award Number: 2017-05474; Stiftelsen Frimurare Barnhuset i Stockholm; Stiftelsen Sunnerdahls Handikappfond; Stiftelsen Promobilia
dc.identifier.citationAsige, Elizabeth, Gillian Saloojee, Carin Andrews, et al. 'Functioning and Activity Outcomes of the Akwenda Intervention Program for Children and Young Adults with Cerebral Palsy in Uganda: A cluster‐randomized Trial', Developmental Medicine and Child Neurology, vol. 67/no. 1, (2025), pp. 87-98.
dc.identifier.issnISSN 0012-1622, 1469-8749
dc.identifier.issnEISSN 1469-8749
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/9739
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc
dc.titleFunctioning and activity outcomes of the Akwenda Intervention Program for children and young adults with cerebral palsy in Uganda: A cluster-randomized trial
dc.typeArticle
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