Factors associated with early inhospital adverse outcome following surgery for acute appendicitis in Uganda: a multicenter cohort

dc.contributor.authorFarhan, Sharif Yusuf
dc.contributor.authorAbraha, Demoz
dc.contributor.authorEdyedu, Isaac
dc.contributor.authorMolen, Selamo Fabrice
dc.contributor.authorMauricio, William
dc.contributor.authorOdong, Samuel Oledo
dc.contributor.authorMugeni, Michael
dc.contributor.authorMuhumuza, Joshua
dc.date.accessioned2024-06-14T07:05:27Z
dc.date.available2024-06-14T07:05:27Z
dc.date.issued2024-05
dc.description.abstractINTRODUCTIONSurgery for acute appendicitis has been associated with significant morbidity. This study aimed to determine the factors associated with early inhospital adverse outcomes following surgery for acute appendicitis in Uganda.METHODSThis was a multicentre, prospective cohort in which early inhospital outcome following surgery for acute appendicitis was assessed at 4 regional referral hospitals in Uganda. The occurrence of complications during the admission period was documented as well as the length of hospital stay. Factors associated with adverse outcomes were determined using Poisson regression.RESULTSOf the 102 patients who underwent surgery for acute appendicitis, the majority were males 79(77.5%) with a mean age of 23.8(SD = 12.5) years. The perforated appendix was seen in 26 (25.5%) patients. Post-operative complications occurred in 21(20.6%) with the commonest being surgical site infection in 19(18.6%) patients. The median length of hospital stay was 3(IQR = 3-4) days with 43(42.2%) staying in hospital for more than 3 days. The presence of anemia (Hb < 8) (aRR = 1.376, CI = 1.159-1.634, P =  < 0.001) and having a perforated appendix (aRR = 1.263, CI = 1.026-1.555, P = 0.027) were independently associated with occurrence of complications while being HIV positive (aRR = 1.379, CI = 1.105-1.721, P = 0.005) and having a perforated appendix (aRR = 1.258, CI = 1.019-1.554, P = 0.033) were independently associated with prolonged hospital stay.CONCLUSIONCommunity education about early presentation is still required in order to reduce the number of patients that present late which should, in turn, reduce the risk of complications and length of hospital stay. MEDLINE - Academicen_US
dc.identifier.citationFarhan, Sharif Yusuf, Demoz Abraha, Isaac Edyedu, et al. 'Factors Associated with Early Inhospital Adverse Outcome Following Surgery for Acute Appendicitis in Uganda: A Multicenter Cohort', Perioperative Medicine (London), vol. 13/no. 1, (2024), pp. 51-51.en_US
dc.identifier.issnISSN 2047-0525
dc.identifier.issnEISSN 2047-0525
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/9563
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.subjectAcute appendicitis, Inhospital early adverse outcomes, Factors, Ugandaen_US
dc.titleFactors associated with early inhospital adverse outcome following surgery for acute appendicitis in Uganda: a multicenter cohorten_US
dc.typeBooken_US
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