Effectiveness of Voluntary Medical Male Circumcision for Human Immunodeficiency Virus Prevention in Rakai, Uganda

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dc.contributor.authorLoevinsohn, Gideon
dc.contributor.authorKigozi, Godfrey
dc.contributor.authorKagaayi, Joseph
dc.contributor.authorWawer, Maria J.
dc.contributor.authorNalugoda, Fred
dc.contributor.authorChang, Larry W.
dc.contributor.authorQuinn, Thomas C.
dc.contributor.authorSerwadda, David
dc.contributor.authorReynolds, Steven J.
dc.contributor.authorNelson, Lisa
dc.contributor.authorMills, Lisa
dc.contributor.authorAlamo, Stella
dc.contributor.authorNakigozi, Gertrude
dc.contributor.authorKabuye, Geoffrey
dc.contributor.authorSsekubugu, Robert
dc.contributor.authorTobian, Aaron A. R.
dc.contributor.authorGray, Ronald H.
dc.contributor.authorGrabowski, M. Kathryn
dc.date.accessioned2022-01-24T21:14:22Z
dc.date.available2022-01-24T21:14:22Z
dc.date.issued2021
dc.description.abstractThe efficacy of voluntary male medical circumcision (VMMC) for human immunodeficiency virus (HIV) prevention in men was demonstrated in 3 randomized trials. This led to the adoption of VMMC as an integral component of the United States President’s Emergency Plan for AIDS Relief (PEPFAR) combination HIV prevention program in sub-Saharan Africa. However, evidence on the individual-level effectiveness of VMMC programs in real-world, programmatic settings is limited. A cohort of initially uncircumcised, non-Muslim, HIV-uninfected men in the Rakai Community Cohort Study in Uganda was followed between 2009 and 2016 during VMMC scale-up. Self-reported VMMC status was collected and HIV tests performed at surveys conducted every 18 months. Multivariable Poisson regression was used to estimate the incidence rate ratio (IRR) of HIV acquisition in newly circumcised vs uncircumcised men.en_US
dc.identifier.citationLoevinsohn, G., Kigozi, G., Kagaayi, J., Wawer, M. J., Nalugoda, F., Chang, L. W., ... & Grabowski, M. K. (2021). Effectiveness of voluntary medical male circumcision for human immunodeficiency virus prevention in Rakai, Uganda. Clinical Infectious Diseases, 73(7), e1946-e1953. DOI: 10.1093/cid/ciaa1533en_US
dc.identifier.other10.1093/cid/ciaa1533
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1532
dc.language.isoenen_US
dc.publisherClinical Infectious Diseasesen_US
dc.subjectCircumcisionen_US
dc.subjectVMMCen_US
dc.subjectCombination HIV preventionen_US
dc.subjectAfricaen_US
dc.subjectPEPFARen_US
dc.titleEffectiveness of Voluntary Medical Male Circumcision for Human Immunodeficiency Virus Prevention in Rakai, Ugandaen_US
dc.typeArticleen_US
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