A new model to monitor the virological efficacy of antiretroviral treatment in resource-poor countries

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dc.contributor.authorColebunders, Robert
dc.contributor.authorKamya, Moses R.
dc.contributor.authorLaurence, John
dc.contributor.authorShihab, Hasan M
dc.contributor.authorSemitala, Fred
dc.contributor.authorLutwama, Fred
dc.contributor.authorLynen, Lut
dc.contributor.authorBakeera-kitaka, Sabrina
dc.contributor.authorSpacek, Lisa
dc.contributor.authorReynolds, Steven J
dc.contributor.authorQuinn, Thomas C
dc.contributor.authorViner, Brant
dc.contributor.authorMayanja-Kizza, Harriet
dc.date.accessioned2021-12-16T05:33:39Z
dc.date.available2021-12-16T05:33:39Z
dc.date.issued2006
dc.description.abstractMonitoring the efficacy of antiretroviral treatment in developing countries is difficult because these countries have few laboratory facilities to test viral load and drug resistance. Those that exist are faced with a shortage of trained staff, unreliable electricity supply, and costly reagents. Not only that, but most HIV patients in resourcepoor countries do not have access to such testing. We propose a new model for monitoring antiretroviral treatment in resource-limited settings that uses patients’ clinical and treatment history, adherence to treatment, and laboratory indices such as haemoglobin level and total lymphocyte count to identify virological treatment failure, and offers patients future treatment options. We believe that this model can make an accurate diagnosis of treatment failure in most patients. However, operational research is needed to assess whether this strategy works in practice.en_US
dc.identifier.citationColebunders, R., Kamya, M. R., Laurence, J., Shihab, H. M. et. al (2006). .A new model to monitor the virological efficacy of antiretroviral treatment in resource-poor countries.Lancet Infectious Diseases, 6: 53–59en_US
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/683
dc.language.isoenen_US
dc.subjectVirological efficacyen_US
dc.subjectAntiretroviral treatmenten_US
dc.subjectHIVen_US
dc.subjectPoor countriesen_US
dc.titleA new model to monitor the virological efficacy of antiretroviral treatment in resource-poor countriesen_US
dc.typeArticleen_US
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