Rethinking Schistosomiasis Vaccine Development

Abstract
There is currently no vaccine against schistosomiasis. With few Schistosoma vaccine candidates in clinical trials, unexplored antigens from the vulnerable schistosomulum should be considered as possible vaccine candidates. In addition, we suggest developing synthetic vesicles as a new delivery vehicle and adjuvant for immunoprophylactic schistosomula vaccine candidates.
Description
Keywords
Schistosoma, Adjuvant, Schistosomula, Delivery, Vaccine candidates, Synthetic vesicles
Citation
Egesa, M., Hoffmann, K. F., Hokke, C. H., Yazdanbakhsh, M., & Cose, S. (2017). Rethinking schistosomiasis vaccine development: synthetic vesicles. Trends in parasitology, 33(12), 918-921.https://doi.org/10.1016/j.pt.2017.07.007https://doi.org/10.1016/j.pt.2017.07.007