Prevalence of cardiovascular risk factors in active tuberculosis in Africa: a systematic review and meta‑analysis

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dc.contributor.authorBaruch Baluku, Joseph
dc.contributor.authorRonald, Olum
dc.contributor.authorBagasha, Peace
dc.contributor.authorOkello, Emmy
dc.contributor.authorBongomin, Felix
dc.date.accessioned2023-01-24T11:02:58Z
dc.date.available2023-01-24T11:02:58Z
dc.date.issued2022
dc.description.abstractPeople with tuberculosis (TB) are at risk of major adverse cardiovascular events. We estimated the prevalence of cardiovascular risk (CVR) factors among people with active TB in Africa. This was a systematic review and meta-analysis of studies from Africa. We searched EMBASE, MEDLINE through PubMed, Web of Science, the Cochrane Central Register of Controlled Trials, mRCTs, Clinical trials.gov, and International Clinical Trials Registry Platform from inception to 31st December 2021. Among 110 eligible studies, 79 (238,316 participants) were included in the meta-analysis for smoking, 67 (52,793 participants) for current alcohol use, 30 (31,450 participants) for hazardous alcohol use, 51 (37,879 participants) for diabetes mellitus (DM), 19 (18,211 participants) for hypertension and 18 (13,910 participants) for obesity. The pooled prevalence was 26.0% (95% confidence interval 22.0–29.0) for smoking, 30.0% (25.0–35.0) for any current alcohol use, 21.0% (17.0–26.0) for hazardous alcohol use, 14.0% (9.0–18.0) for hypertension, 7.0% (6.0–9.0) for DM, and 4.0% (2.0–5.0) for obesity. Costeffective strategies are needed to screen for CVR factors among people with active TB in Africa.en_US
dc.identifier.citationBaluku, J. B., Ronald, O., Bagasha, P., Okello, E., & Bongomin, F. (2022). Prevalence of cardiovascular risk factors in active tuberculosis in Africa: a systematic review and meta-analysis. Scientific Reports, 12(1), 16354. https://doi.org/10.1038/s41598-022-20833-0en_US
dc.identifier.urihttps://doi.org/10.1038/s41598-022-20833-0
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7147
dc.language.isoenen_US
dc.publisherScientific Reportsen_US
dc.subjectCardiovascular risk factorsen_US
dc.subjectTuberculosisen_US
dc.subjectAfricaen_US
dc.titlePrevalence of cardiovascular risk factors in active tuberculosis in Africa: a systematic review and meta‑analysisen_US
dc.typeArticleen_US
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