Burden of tinea capitis among children in Africa: protocol for a systematic review and meta-analysis of observational studies, 1990–2020
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Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
BMJ Open
Abstract
Tinea capitis is the most common form of
dermatophytosis among children, contributing significantly
to the global burden of skin and hair infections. However,
an accurate account of its burden in Africa, where
most cases are thought to occur, is lacking. We aim
to systematically evaluate the burden, aetiology and
epidemiological trend of tinea capitis among children over
a 30-year
period in Africa.
Methods and analysis A systematic review will be
conducted using Embase, PubMed, African Journals Online,
Web of Science and the Cochrane Library of Systematic
Review. These resources will be used to identify studies
published between 1990 and December 2020, which
report the prevalence, aetiology and trend of tinea capitis
among children younger than 18 years in Africa. Articles in
English and French will be considered. Two independent
reviewers will screen the articles for eligibility, and
any discrepancies will be resolved by discussion and
consensus between the authors. Methodological quality
of all studies will be assessed and critically appraised.
We will perform a metaregression to assess the impact of
study characteristics on heterogeneity and also to correct
the meta-analytical
estimates for biases. A qualitative
synthesis will be performed, and STATA V.16.0 software
will be used to estimate the pooled prevalence and
aetiology of tinea capitis. The Mann-Kendall
trend test will
be use to evaluate the trend in the prevalence of tinea
capitis over the study period.
Ethics and dissemination Ethical approval from an
institutional review board or research ethics committee is
not required for this systematic review and meta-analysis.
The results will be published in a peer-reviewed
journal
and presented in conferences.
Description
Keywords
Burden, Tinea capitis, Children, Africa, Observational studies
Citation
Bongomin F, Olum R, Nsenga L, et al. Burden of tinea capitis among children in Africa: protocol for a systematic review and meta-analysis of observational studies, 1990–2020. BMJ Open 2020;10:e041230. doi:10.1136/ bmjopen-2020-041230