Adherence to oral HIV pre-exposure prophylaxis among female sex workers in Kampala, Uganda
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
African Health Sciences
Abstract
In Kampala Uganda, female sex workers (FSWs) have high HIV prevalence (33%). Oral PrEP is a novel
HIV prevention intervention that offers hope to decrease HIV incidence in key populations especially among FSWs. Studies
have shown that with poor adherence, oral PrEP has no efficacy, and therefore adherence to PrEP is critical among FSWs
to maximize HIV prevention. However, implementation data on adherence to PrEP among FSWs is limited so this study
sought to assess adherence to PrEP. Specifically, we sought to 1) determine the level of adherence to PrEP among FSWs,
and 2) determine factors associated with PrEP adherence.
Methods: This cross-sectional study was conducted from November to December 2018; 126 FSWs using PrEP were interviewed
using a questionnaire. Adherence was categorically defined as high adherence and low adherence. Logistic regression
was done.
Results: Using long-term contraception methods (OR 0.06, 95% CI: 0.04-0.77) and not using condoms with clients (OR
0.07, 95% CI: 0.01-0.42) were negatively associated with high PrEP adherence.
Conclusion: Barriers to PrEP adherence need to be addressed for successful PrEP implementation to improve adherence
going forward. Service care providers should reinforce positive behaviors such as use of condoms devotedly during PrEP
breaks.
Description
Keywords
Oral PrEP, Adherence, Female sex workers
Citation
Nalukwago GK, Isunju JB, Muwonge T, Katairo T, Bunani N, Semitala F, et al. Adherence to oral HIV pre-exposure prophylaxis among female sex workers in Kampala, Uganda. Afri Health Sci. 2021;21(3). 1048-1058. https://dx.doi.org/10.4314/ahs.v21i3.12