Draft genome sequence of Solanum aethiopicum provides insights into disease resistance, drought tolerance, and the evolution of the genome

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dc.contributor.authorSong, Bo
dc.contributor.authorSong, Yue
dc.contributor.authorFu, Yuan
dc.contributor.authorBalyejusa Kizito, Elizabeth
dc.contributor.authorNdagire Kamenya, Sandra
dc.contributor.authorNahamya Kabod, Pamela
dc.contributor.authorLiu, Huan
dc.contributor.authorMuthemba, Samuel
dc.contributor.authorKariba, Robert
dc.contributor.authorNjuguna, Joyce
dc.contributor.authorMaina, Solomon
dc.contributor.authorStomeo, Francesca
dc.contributor.authorDjikeng, Appolinaire
dc.contributor.authorHendre, Prasad S.
dc.contributor.authorChen, Xiaoli
dc.contributor.authorChen, Wenbin
dc.contributor.authorLi1, Xiuli
dc.contributor.authorSun, Wenjing
dc.contributor.authorWang, Sibo
dc.contributor.authorCheng, Shifeng
dc.contributor.authorMuchugi, Alice
dc.contributor.authorJamnadass, Ramni
dc.contributor.authorShapiro, Howard-Yana
dc.contributor.authorVan Deynze, Allen
dc.contributor.authorYang, Huanming
dc.contributor.authorWang, Jian
dc.contributor.authorXu, Xun
dc.contributor.authorAchieng Odeny, Damaris
dc.contributor.authorLiu, Xin
dc.date.accessioned2022-12-29T15:18:45Z
dc.date.available2022-12-29T15:18:45Z
dc.date.issued2019
dc.description.abstractThe African eggplant (Solanum aethiopicum) is a nutritious traditional vegetable used in many African countries, including Uganda and Nigeria. It is thought to have been domesticated in Africa from its wild relative, Solanum anguivi. S. aethiopicum has been routinely used as a source of disease resistance genes for several Solanaceae crops, including Solanum melongena. A lack of genomic resources has meant that breeding of S. aethiopicum has lagged behind other vegetable crops. Results: We assembled a 1.02-Gb draft genome of S. aethiopicum, which contained predominantly repetitive sequences (78.9%). We annotated 37,681 gene models, including 34,906 protein-coding genes. Expansion of disease resistance genes was observed via 2 rounds of amplification of long terminal repeat retrotransposons, which may have occurred ∼1.25 and 3.5 million years ago, respectively. By resequencing 65 S. aethiopicum and S. anguivi genotypes, 18,614,838 single-nucleotide polymorphisms were identified, of which 34,171 were located within disease resistance genes. Analysis of domestication and demographic history revealed active selection for genes involved in drought tolerance in both “Gilo” and “Shum” groups. A pan-genome of S. aethiopicum was assembled, containing 51,351 protein-coding genes; 7,069 of these genes were missing from the reference genome. Conclusions: The genome sequence of S. aethiopicum enhances our understanding of its biotic and abiotic resistance. The single-nucleotide polymorphisms identified are immediately available for use by breeders. The information provided here will accelerate selection and breeding of the African eggplant, as well as other crops within the Solanaceae family.en_US
dc.identifier.citationSong, B., Song, Y., Fu, Y., Kizito, E. B., Kamenya, S. N., Kabod, P. N., ... & Liu, X. (2019). Draft genome sequence of Solanum aethiopicum provides insights into disease resistance, drought tolerance, and the evolution of the genome. GigaScience, 8(10), giz115.en_US
dc.identifier.urihttps://academic.oup.com/gigascience/article-abstract/8/10/giz115/5579996
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/6755
dc.language.isoenen_US
dc.publisherGigaScienceen_US
dc.subjectSolanum aethiopicumen_US
dc.subjectAfrican eggplanten_US
dc.subjectSolanum anguivien_US
dc.subjectLTR-Rsen_US
dc.subjectBiotic stressen_US
dc.subjectDrought Toleranceen_US
dc.titleDraft genome sequence of Solanum aethiopicum provides insights into disease resistance, drought tolerance, and the evolution of the genomeen_US
dc.typeArticleen_US
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