Intra-abdominal hypertension in severe burns: prevalence, incidence and mortality in a sub-Saharan African hospital

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dc.contributor.authorMbiine, Ronald
dc.contributor.authorAlenyo, Rose
dc.contributor.authorKobusingye, Olive
dc.contributor.authorKuteesa, Job
dc.contributor.authorNakanwagi, Cephas
dc.contributor.authorMonka Lekuya, Hervé
dc.contributor.authorKituuka, Olivia
dc.contributor.authorGalukande, Moses
dc.date.accessioned2021-12-14T09:22:31Z
dc.date.available2021-12-14T09:22:31Z
dc.date.issued2017
dc.description.abstractSevere burns have been shown to be a risk factor for developing intra-abdominal hypertension (IAH). Fluid resuscitation practices used in burns management further predispose patients to intra-abdominal hypertension. The mortality associated with IAH in severe burns is estimated to be more than 74.5% once organ dysfunction occurs. Despite 95% of all burns occurring in Low and Middle income countries (LMIC), there is paucity of published data on this topic in sub-Saharan Africa. Objectives: To determine the prevalence, incidence, organ dysfunction and mortality of intra-abdominal hypertension among severe burns patients. Methods: A prospective cohort study was conducted over a 6 months period in the Burns Unit of Mulago National Referral Hospital. Patients of all age groups with burns ≥25% and 20% in adults and children respectively were recruited and followed up for 7 days or until death occurred. Patients with burns older than 48 hours were excluded. The outcome variables were intra-abdominal pressure, organ dysfunction and seven day mortality. Results: Of all the 335 burns patients admitted, 64 patients met the inclusion criteria. The overall prevalence of IAH was 57.8% while the prevalence in the children and adults was 54.5% and 61.3% respectively. The incidence of IAH was 13.1 cases/100 person days with the incidence in adults being twice that of the children. The one week mortality of patients with IAH was 82.6% with the risk of dying being 3.34 (p=0.0035) and seven day survival being less than 50%. Conclusion: One in two patients with severe burns exceeding 20% or 25% in children or adults respectively developed IAH. Adults had a higher prevalence and incidence of IAH. Mortality associated with IAH exceeded 80%.en_US
dc.identifier.citationMbiine, R., Alenyo, R., Kobusingye, O., Kuteesa, J., Nakanwagi, C., Lekuya, H. M., ... & Galukande, M. (2017). Intra-abdominal hypertension in severe burns: prevalence, incidence and mortality in a sub-Saharan African hospital. International journal of burns and trauma, 7(6), 80.en_US
dc.identifier.issn2160-2026
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/470
dc.language.isoenen_US
dc.publisherInternational journal of burns and traumaen_US
dc.subjectIntra-abdominal hypertensionen_US
dc.subjectsevere burnsen_US
dc.subjectabdominal compartment syndromeen_US
dc.subjectsub-Saharan Africaen_US
dc.subjectUgandaen_US
dc.subjectAfricaen_US
dc.subjectoutcomeen_US
dc.subjectmortalityen_US
dc.titleIntra-abdominal hypertension in severe burns: prevalence, incidence and mortality in a sub-Saharan African hospitalen_US
dc.typeArticleen_US
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