Characterization of Asthma and Its Determinants in Ethiopia: Part of the African Severe Asthma Project (ASAP)

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dc.contributor.authorBekel, Amsalu
dc.contributor.authorHaile, Tewodros
dc.contributor.authorMekekasha, Amha
dc.contributor.authorFuad, Oumer
dc.contributor.authorMuttamba, Winters
dc.contributor.authorMugenyi, Levi
dc.contributor.authorKatagira, Wincey
dc.contributor.authorNyale, George
dc.contributor.authorLugogo, Njira
dc.contributor.authorWorodria, William
dc.contributor.authorAanyu, Hellen T.
dc.contributor.authorJoloba, Moses
dc.contributor.authorJong, Corina de
dc.contributor.authorMakumbi, Fred
dc.contributor.authorMolen, Thys van der
dc.contributor.authorChakaya, Jeremiah
dc.contributor.authorKirenga, Bruce J
dc.contributor.authorYimer, Getenet
dc.date.accessioned2021-12-09T14:45:39Z
dc.date.available2021-12-09T14:45:39Z
dc.date.issued2021
dc.description.abstractAsthma is a major public health problem globally affecting 339 million people with 300,000 annual death. African Severe Asthma Program was a multi-country prospective cohort study designed to characterize severe asthma in three African countries, Ethiopia, Uganda and Kenya. In this study, we describe the baseline characteristics and disease severity among asthmatics enrolled in the Ethiopia site of African Severe Asthma Program. Asthmatics seen at Tikur Anbessa Specialized Hospital from August 2016 to May 2018 were studied. Asthma was diagnosed based on symptoms and spirometry. Baseline demographic and clinical data were collected using a structured questionnaire. Standardized research tools were used to assess asthma severity, asthma control and asthma quality of life. A total of 419 asthmatic patients were enrolled in the study; the mean age for the group was 52 ± 8 years and 58.2 % were female. The majority of the participants, 365 (87.2%), had a prior diagnosis of asthma with a median (IQR) age at first diagnosis of 29 (IQR: 22 - 36) years. A family history of asthma was present in 149 (35.6%) subjects. Current or previous cigarette smoking was reported in 8.6% of the participants. Overall, 93.8% of the participants reported uncontrolled asthma symptoms (ACQ >1.5). More than half of the patients, had severe persistent asthma and 35% presented with one or more comorbidities. Conclusions: In Ethiopia, asthmatics presenting to a tertiary care hospital were characterized as predominantly female with late onset disease, poor control, and associated comorbidities. Key Words: Asthma, Characteristics, determinants and Severeen_US
dc.identifier.citationBekele, A. (2021). Characterization of Asthma and Its Determinants in Ethiopia: Part of the African Severe Asthma Project (ASAP). Ethiopian Medical Journal, 59(02). Retrieved from https://emjema.org/index.php/EMJ/article/view/1738en_US
dc.identifier.issn0014-1755
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/232
dc.language.isoenen_US
dc.publisherEthiopian Medical Journalen_US
dc.titleCharacterization of Asthma and Its Determinants in Ethiopia: Part of the African Severe Asthma Project (ASAP)en_US
dc.typeArticleen_US
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