A systematic review of modeling and simulation approaches in designing targeted treatment technologies for Leukemia Cancer in low and middle income countries

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dc.contributor.authorFenekansi Kiwumulo, Henry
dc.contributor.authorMuwonge, Haruna
dc.contributor.authorIbingira, Charles
dc.contributor.authorKirabira, John Baptist
dc.contributor.authorTamale Ssekitoleko, Robert
dc.date.accessioned2021-12-17T12:18:19Z
dc.date.available2021-12-17T12:18:19Z
dc.date.issued2021
dc.description.abstractVirtual experimentation is a widely used approach for predicting systems behaviour especially in situations where resources for physical experiments are very limited. For example, targeted treatment inside the human body is particularly challenging, and as such, modeling and simulation is utilised to aid planning before a specific treatment is administered. In such approaches, precise treatment, as it is the case in radiotherapy, is used to administer a maximum dose to the infected regions while minimizing the effect on normal tissue. Complicated cancers such as leukemia present even greater challenges due to their presentation in liquid form and not being localised in one area. As such, science has led to the development of targeted drug delivery, where the infected cells can be specifically targeted anywhere in the body.en_US
dc.identifier.citationKiwumulo, H. F., Muwonge, H., Ibingira, C., Kirabira, J. B., & Ssekitoleko, R. T. (2021). A systematic review of modeling and simulation approaches in designing targeted treatment technologies for Leukemia Cancer in low and middle income countries. Mathematical Biosciences and Engineering, 18(6), 8149-8173. DOI: 10.3934/mbe.2021404en_US
dc.identifier.other10.3934/mbe.2021404
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/731
dc.language.isoenen_US
dc.publisherMathematical Biosciences and Engineeringen_US
dc.subjectModeling and simulationen_US
dc.subjectLMICsen_US
dc.subjectLeukemia treatmenten_US
dc.subjectTargeted drug deliveryen_US
dc.subjectNanomedicineen_US
dc.subjectMagnetic strengthen_US
dc.titleA systematic review of modeling and simulation approaches in designing targeted treatment technologies for Leukemia Cancer in low and middle income countriesen_US
dc.typeArticleen_US
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