Harnessing Pharmacogenomics to Tackle Resistance to the “Nucleoside Reverse Trancripatse Inhibitor” Backbone of Highly Active Antiretroviral Therapy in Resource Limited Settings
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Date
2008
Journal Title
Journal ISSN
Volume Title
Publisher
The open AIDS journal
Abstract
The highest burden of the human immunodeficiency virus (HIV) epidemic is concentrated in the sub-Saharan region. Over 70% of all global HIV infections have been found to occur here [1]. Despite the earlier policy and patent controversies surrounding the use of highly active antiretroviral therapy (HAART) within this setting, HAART has widely gained application here [2]. This access to HAART can be mainly attributed to several advocacy and funding avenues [2-4]. Specifically, the World Bank and its global partners, in particular, with commitment by the G8, have ensured that several countries within this setting can meet the WHO 3’by 5” target of treating 3 million by 2005 [3,4].
Description
Keywords
Acquired immunodeficiency syndrome(AIDS), Highly active antiretroviral therapy (HAART), Human immunodeficiency virus (HIV), Drug resistance
Citation
Wayengera, M., Kajumbula, H., & Byarugaba, W. (2008). Harnessing Pharmacogenomics to Tackle Resistance to the “Nucleoside Reverse Trancripatse Inhibitor” Backbone of Highly Active Antiretroviral Therapy in Resource Limited Settings. The open AIDS journal , 2 , 78.