Prevalence of Group a Streptococcus Pharyngeal Carriage and Clinical Manifestations in School Children aged 5–15 yrs in Wakiso District, Uganda
| dc.contributor.author | Nayiga, Irene | |
| dc.contributor.author | Okello, Emmy | |
| dc.contributor.author | Lwabi, Peter | |
| dc.contributor.author | Ndeezi, Grace | |
| dc.date.accessioned | 2025-01-28T17:38:53Z | |
| dc.date.available | 2025-01-28T17:38:53Z | |
| dc.date.issued | 2017-04-05 | |
| dc.description.abstract | Beta-hemolytic streptococci carrier rates in children living in low-income countries are high ranging from 10 to 50%. Although most of these children are asymptomatic, they are a reservoir and pose a risk of transmission. The aim of this study was to determine the prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school going children in Wakiso district, Uganda. A cross sectional study targeting children age 5–15 years in primary schools in one sub-county of Wakiso district was carried out. Three hundred and sixty-six children from five primary schools were enrolled and evaluated for group a streptococcus (GAS) carriage. A semi-structured questionnaire was used to collect data that included social demographics, school environment and clinical findings. For every enrolled child a throat swab was taken and cultured for GAS and blood was drawn for anti-streptolysin-O titres. Analysis of data was done using STATA. The prevalence of GAS carriage was 16%. The children with GAS positive cultures were mainly females. The factor associated with GAS carriage was the school location, with peri-urban schools more likely to have children with GAS compared to rural schools; AOR 2.48 (95% CI: 1.01 – 6.11), P = 0.049. There was no significant difference between the characteristic of children with GAS positive verses GAS negative throat swab cultures. There is a high prevalence of GAS pharyngeal carriage among children aged 5–15 years attending primary schools in Wakiso District, Uganda. | |
| dc.identifier.citation | Nayiga, I., Okello, E., Lwabi, P., & Ndeezi, G. (2017). Prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school children aged 5–15 yrs in Wakiso District, Uganda. BMC Infectious Diseases, 17, 1-8.https://doi.org/10.1186/s12879-017-2353-5 | |
| dc.identifier.other | https://doi.org/10.1186/s12879-017-2353-5 | |
| dc.identifier.uri | https://nru.uncst.go.ug/handle/123456789/9874 | |
| dc.language.iso | en | |
| dc.publisher | BMC Infectious Diseases | |
| dc.title | Prevalence of Group a Streptococcus Pharyngeal Carriage and Clinical Manifestations in School Children aged 5–15 yrs in Wakiso District, Uganda | |
| dc.type | Article |