A Cost-Effectiveness Analysis of a Pediatric Operating Room in Uganda

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dc.contributor.authorYap, Ava
dc.contributor.authorMuzira, Arlene
dc.contributor.authorCheung, Maija
dc.contributor.authorHealy, James
dc.contributor.authorKakembo, Nasser
dc.contributor.authorKisa, Phyllis
dc.contributor.authorCunningham, David
dc.contributor.authorYoungson, George
dc.contributor.authorSekabira, John
dc.contributor.authorYaesoubi, Reza
dc.contributor.authorOzgediz, Doruk
dc.date.accessioned2022-03-14T08:33:02Z
dc.date.available2022-03-14T08:33:02Z
dc.date.issued2018
dc.description.abstractThis study examines the cost-effectiveness of constructing a dedicated pediatric operating room (OR) in Uganda, a country where access to surgical care is limited to 4 pediatric surgeons serving a population of over 20 million children under 15 years of age.A simulation model using a decision tree template was developed to project the cost and disability-adjusted life-years saved by a pediatric OR in a low-income setting. Parameters are informed by patient outcomes of the surgical procedures performed. Costs of the OR equipment and a literature review were used to calculate the incremental cost-effectiveness ratio of a pediatric OR. One-way and probabilistic sensitivity analysis were performed to assess parameter uncertainty. Economic monetary benefit was calculated using the value of a statistical life approach.A pediatric OR averted a total of 6,447 disability-adjusted life-years /year (95% uncertainty interval 6,288–6,606) and cost $41,182/year (UI 40,539–41,825) in terms of OR installation. The pediatric operating room had an incremental cost-effectiveness ratio of $6.39 per disability-adjusted life-year averted (95% uncertainty interval of 6.19-6.59), or $397.95 (95% uncertainty interval of 385.41-410.67) per life saved based on the country's average life expectancy in 2015. These values were well within the WHO guidelines of cost-effectiveness threshold. The net economic benefit amounted to $5,336,920 for a year of operation, or $16,371 per patient. The model remained robust with one-way and probabilistic sensitivity analyses.The construction of a pediatric operating room in Uganda is a cost-effective and worthwhile investment, endorsing future decisions to enhance pediatric surgical capacity in the resource-limited settings of Sub-Saharan Africa.en_US
dc.identifier.citationYap, A., Muzira, A., Cheung, M., Healy, J., Kakembo, N., Kisa, P., ... & Ozgediz, D. (2018). A cost-effectiveness analysis of a pediatric operating room in Uganda. Surgery, 164(5), 953-959.https://doi.org/10.1016/j.surg.2018.03.023en_US
dc.identifier.issn0039-6060
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/2801
dc.language.isoenen_US
dc.publisherSurgeryen_US
dc.titleA Cost-Effectiveness Analysis of a Pediatric Operating Room in Ugandaen_US
dc.typeArticleen_US
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