Green synthesis and characterization of iron‑oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries
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Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
BMC Research Notes
Abstract
Green synthesized iron(III) oxide (
Fe3O4) nanoparticles are gaining appeal in targeted drug delivery
systems because of their low cost, fast processing and nontoxicity. However, there is no known research work
undertaken in the production of green synthesized nano-particles from the Ugandan grown Moringa Oleifera (MO).
This study aims at exploring and developing an optimized protocol aimed at producing such nanoparticles from the
Ugandan grown Moringa.
Results: While reducing ferric chloride solution with Moringa oleifera leaves, Iron oxide nanoparticles (
Fe3O4-NPs)
were synthesized through an economical and completely green biosynthetic method. The structural properties of
these Fe3O4-
NPs were investigated by Ultra Violet–visible (UV–Vis) spectrophotometry, X-ray diffraction (XRD), energy
dispersive X-ray spectroscopy (EDX) and scanning electron microscopy (SEM). These nanoparticles exhibited UV–visible
absorption peaks at 225 nm (nm) for the sixth dilution and 228 nm for the fifth dilution which indicated that the
nanoparticles were photosensitive and the SEM study confirmed the spherical nature of these nanoparticles. The
total synthesis time was approximately 5 h after drying the moringa leaves, and the average particle size was approximately
16 nm. Such synthesized nanoparticles can potentially be useful for drug delivery, especially in Low and Middle
Income Countries (LMICs).
Description
Keywords
Green synthesis, Bio-compatible, Iron oxide nanoparticles, Moringa oleifera
Citation
Kiwumulo, H. F., Muwonge, H., Ibingira, C., Lubwama, M., Kirabira, J. B., & Ssekitoleko, R. T. (2022). Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries. BMC Research Notes, 15(1), 1-8. https://doi.org/10.1186/s13104-022-06039-7