Virologic Response to First-Line Efavirenz- or Nevirapine-Based Anti-Retroviral Therapy in HIV-Infected African Children

Simple item page
dc.contributor.authorKekitiinwa, Adeodata
dc.contributor.authorSzubert, Alexander J.
dc.contributor.authorKaturamu, Richard
dc.contributor.authorMusiime, Victor
dc.contributor.authorKitaka, Sabrina Bakeera
dc.contributor.authorWalker, Ann Sarah
dc.contributor.authorSenfuma, Oscar
dc.contributor.authorGibb, Diana M.
dc.date.accessioned2023-02-21T16:00:22Z
dc.date.available2023-02-21T16:00:22Z
dc.date.issued2017
dc.description.abstractPoorer virologic response to nevirapine vs efavirenz-based antiretroviral therapy (ART) has been reported in adult systematic reviews and pediatric studies. We compared drug discontinuation and viral load (VL) response in ART-naïve Ugandan/Zimbabwean children ≥3 years of age initiating ART with clinician-chosen nevirapine vs efavirenz in the ARROW trial. Predictors of suppression <80, <400 and <1000 copies/ml at 36, 48 and 144 weeks were identified using multivariable logistic regression with backwards elimination (p=0.1).en_US
dc.identifier.citationKekitiinwa, A., Szubert, A. J., Spyer, M., Katuramu, R., Musiime, V., Mhute, T., ... & ARROW Trial Team. (2017). Virologic response to first-line efavirenz-or nevirapine-based anti-retroviral therapy in HIV-infected African children. The Pediatric infectious disease journal, 36(6), 588.https://doi.org/10.1097%2FINF.0000000000001505en_US
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7908
dc.language.isoenen_US
dc.publisherThe Pediatric infectious disease journalen_US
dc.subjectHIVen_US
dc.subjectchildrenen_US
dc.subjectantiretroviral therapyen_US
dc.subjectviral loaden_US
dc.subjectNNRTIen_US
dc.titleVirologic Response to First-Line Efavirenz- or Nevirapine-Based Anti-Retroviral Therapy in HIV-Infected African Childrenen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Virologic Response to First-Line Efavirenz- or Nevirapine-Based Anti-Retroviral Therapy in HIV-Infected African Children.pdf
Size:
321.22 KB
Format:
Adobe Portable Document Format
Description:
Virologic Response to First-Line Efavirenz- or Nevirapine-Based Anti-Retroviral Therapy in HIV-Infected African Children
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medical and Health Sciences