Solubility tests and the peripheral blood film method for screening for sickle-cell disease: A cost benefit analysis
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Date
2009
Journal Title
Journal ISSN
Volume Title
Publisher
South African Medical Journal
Abstract
To determine the cost benefit of screening for sicklecell disease among infants at district health centres in Uganda using sickling, solubility tests and the peripheral blood film method.
Methods. Pilot screening services were established at district health centres. Cost benefit analysis (CBA) was performed in
four scenarios: A1 – where there are no sickle-cell screening services at district health centres and all children are referred either to Mulago national referral hospital or A2 – a regional hospital for haemoglobin (Hb) electrophoresis; B1 – when there are screening services at district health centres, only positive samples are taken either to Mulago Hospital or B2 – the regional hospital for confirmation using haemoglobin electrophoresis. Calculations were done in Uganda shillings (USh).
Description
Keywords
Peripheral blood film method, Screening, Sickle-cell diseas
Citation
Okwi, A. L., Ocaido, M., & Byarugaba, W. (2009). Solubility tests and the peripheral blood film method for screening for sickle-cell disease: A cost benefit analysis. South African Medical Journal, 99(12).