Uptake of intermittent preventive treatment of malaria in pregnancy using sulfadoxine-pyrimethamine (IPTp-SP) in Uganda: a national survey
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Date
2022-10
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BioMed Central Ltd
Abstract
Abstract
Background: In spite of the missed opportunities of sulfadoxine-pyrimethamine (IPTp-SP) in Uganda, scanty literature exist on malaria in pregnancy. To date, empirical national study utilizing the 2018-19 Uganda Malaria Indicator
Survey to explore predictors of attaining three or more doses of IPTp-SP in the country is non-existent. This study
investigated the factors afecting uptake of three or more IPTp-SP doses as recommended by the World Health
Organization.
Methods: Data from the 2018–2019 Uganda Malaria Indicator Survey (2018-19 UMIS) was analysed. Adequate uptake
of intermittent preventive therapy with IPTp-SP was the dependent variable for this study. Weighted frequencies and
percentages were used to present the proportion of women who had adequate IPTp-SP uptake or otherwise with
respect to the independent variables. A three-level multilevel logistic regression was ftted. The Bayesian Deviance
Information Criterion (DIC) was used in determining the goodness of ft of all the models.
Results: Less than half of the surveyed women had three or more IPTp-SP doses during their last pregnancies
(45.3%). Women aged 15–19 had less odds of receiving at least three IPTp-SP doses compared to those aged 45–49
[aOR=0.42, Crl=0.33–0.98]. Poor women [aOR=0.80, Crl=0.78–0.91] were less likely to have three or more doses of
IPTp-SP relative to rich women. Most disadvantaged regions were aligned with less likelihood of three or more IPTpSP uptake [aOR=0.59, CI=0.48–0.78] compared to least disadvantaged regions. The variation in uptake of three or
more IPTp-SP doses was substantial at the community level [σ2=1. 86; Crl=11.12–2.18] than regional level [σ2=1.13;
Crl=1.06–1.20]. About 18% and 47% disparity in IPTp-SP uptake are linked to region and community level factors
respectively.
Conclusion: IPTp-SP interventions need to refect broader community and region level factors in order to wane the
high malaria prevalence in Uganda. Contextually responsive behavioural change communication interventions are
required to invoke women’s passion to achieve the recommended dosage.
Keywords: Malaria, Pregnancy, Public health, Maternal health, Uganda
Description
Keywords
Malaria, Pregnancy, Public health, Maternal health, Uganda
Citation
Ameyaw, Edward Kwabena. 'Uptake of Intermittent Preventive treatment of Malaria in Pregnancy using Sulfadoxine-Pyrimethamine (IPTp-SP) in Uganda: A National Survey', Malaria Journal, vol. 21/no. 1, (2022), pp. 285-10.