The Lake Victoria Island Intervention Study on Worms and Allergy-related diseases (LaVIISWA): Study Protocol for a Randomised Controlled Trial

dc.contributor.authorNampijja, Margaret
dc.contributor.authorWebb, Emily L.
dc.contributor.authorKaweesa, James
dc.contributor.authorKizindo, Robert
dc.contributor.authorNamutebi, Milly
dc.contributor.authorNakazibwe, Esther
dc.contributor.authorOduru, Gloria
dc.contributor.authorKabuubi, Prossy
dc.contributor.authorKabagenyi, Joyce
dc.contributor.authorKizito, Dennison
dc.contributor.authorMuhangi, Lawrence
dc.contributor.authorAkello, Mirriam
dc.contributor.authorVerweij, Jaco J.
dc.contributor.authorNerima, Barbara
dc.contributor.authorTukahebwa, Edridah
dc.contributor.authorElliott, Alison M.
dc.date.accessioned2023-03-27T11:43:22Z
dc.date.available2023-03-27T11:43:22Z
dc.date.issued2015
dc.description.abstractThe Hygiene Hypothesis proposes that infection exposure protects against inflammatory conditions. Helminths possess allergen-like molecules and may specifically modulate allergy-related immunological pathways to inhibit responses which protect against them. Mass drug administration is recommended for helminth-endemic communities to control helminth-induced pathology, but may also result in increased rates of inflammation-mediated diseases in resource-poor settings. Immunological studies integrated with implementation of helminth control measures may elucidate how helminth elimination contributes to ongoing epidemics of inflammatory diseases. We present the design of the Lake Victoria Island Intervention Study on Worms and Allergy-related diseases (LaVIISWA), a cluster-randomised trial evaluating the risks and benefits of intensive versus standard anthelminthic treatment for allergy-related diseases and other health outcomes.en_US
dc.identifier.citationNampijja, M., Webb, E. L., Kaweesa, J., Kizindo, R., Namutebi, M., Nakazibwe, E., ... & Elliott, A. M. (2015). The Lake Victoria Island Intervention Study on Worms and Allergy-related diseases (LaVIISWA): study protocol for a randomised controlled trial. Trials, 16(1), 1-14.https://doi.org/10.1186/s13063-015-0702-5en_US
dc.identifier.issn1745-6215
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8313
dc.language.isoenen_US
dc.publisherTrialsen_US
dc.subjectHelminthsen_US
dc.subjectAnthelminthic treatmenten_US
dc.subjectAllergyen_US
dc.subjectWheezeen_US
dc.titleThe Lake Victoria Island Intervention Study on Worms and Allergy-related diseases (LaVIISWA): Study Protocol for a Randomised Controlled Trialen_US
dc.typeArticleen_US
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