Antiretroviral Therapy is Highly Effective Against Incident Hepatitis B Disease Acquisition Among HIV-Infected Adults in Rakai, Uganda

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dc.contributor.authorSeremba, Emmanuel
dc.contributor.authorSsempijja, Victor
dc.contributor.authorKalibbala, Sarah
dc.contributor.authorGray, Ronald
dc.contributor.authorWawer, Maria
dc.contributor.authorNalugoda, Fred
dc.contributor.authorCasper, Corey
dc.contributor.authorPhipps, Warren T.
dc.contributor.authorOcama, Ponsiano
dc.contributor.authorThomas, David L.
dc.contributor.authorReynolds, Steven J.
dc.date.accessioned2022-01-20T20:58:43Z
dc.date.available2022-01-20T20:58:43Z
dc.date.issued2016
dc.description.abstractCo-infection with HepatitisB(HBV) and HIV iscommonin sub-Saharan Africa (SSA) and accelerates progression of liver disease to cirrhosis, hepatocellular carcinoma (HCC) andother complications. About 60% of HCC in Africa is attributed to HBV. In Uganda, 80% of HCC patients have HBVand20%have HIV/HBV coinfection.HCCis the 4th commonest cancer among Ugandan males and the 6th commonest in females. It is almost always a fatal malignancy in SSA. Prevention of HBV is best achieved through vaccination. Vaccination of HIV-infected adults for HBV is standard of care in developed countries but not in SSA where HBV is believed to be acquired in childhood and where there is lack of HBV incidence data. We investigated the incidence and risk factors associated with HBV among HIV-infected adults in Rakai, Uganda.en_US
dc.identifier.citationSeremba, E., Ssempijja, V., Kalibbala, S., Gray, R., Wawer, M., Nalugoda, F., ... & Reynolds, S. J. (2016). Antiretroviral Therapy is Highly Effective Against Incident Hepatitis B Disease Acquisition Among HIV-Infected Adults in Rakai, Uganda. DOI: 10.1200/JGO.2016.004044en_US
dc.identifier.other10.1200/JGO.2016.004044
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1362
dc.language.isoenen_US
dc.publisherAmerican Society of Clinical Oncologyen_US
dc.subjectTherapyen_US
dc.subjectHepatitis B Disease Acquisitionen_US
dc.subjectHIV-Infected Adultsen_US
dc.subjectUgandaen_US
dc.titleAntiretroviral Therapy is Highly Effective Against Incident Hepatitis B Disease Acquisition Among HIV-Infected Adults in Rakai, Ugandaen_US
dc.typeArticleen_US
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