Correlates of uptake of optimal doses of sulfadoxine‑pyrimethamine for prevention of malaria during pregnancy in East‑Central Uganda
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Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
Malaria Journal
Abstract
In 2012, the World Health Organization recommended that pregnant women in malaria-endemic
countries complete at least three (optimal) doses of intermittent preventive treatment (IPTp) using sulfadoxinepyrimethamine
(SP) to prevent malaria and related adverse events during pregnancy. Uganda adopted this recommendation,
but uptake remains low in East-Central and information to explain this low uptake remains scanty. This
analysis determined correlates of uptake of optimal doses of IPTp-SP in East-Central Uganda.
Methods: This was a secondary analysis of the 2016 Uganda Demographic Health Survey data on 579 women
(15–49 years) who attended at least one antenatal care (ANC) visit and had a live birth within 2 years preceding the
survey. Uptake of IPTp-SP was defined as optimal if a woman received at least three doses; partial if they received 1–2
doses or none if they received no dose. Multivariate analysis using multinomial logistic regression was used to determine
correlates of IPTp-SP uptake.
Results: Overall, 22.3% of women received optimal doses of IPTp-SP, 48.2% partial and 29.5% none. Attending ANC
at a lower-level health centre relative to a hospital was associated with reduced likelihood of receiving optimal doses
of IPTp-SP. Belonging to other religious faiths relative to Catholic, belonging to a household in the middle relative to
poorest wealth index, and age 30 and above years relative to 25–29 years were associated with higher likelihood of
receiving optimal doses of IPTp-SP.
Conclusions: In East-Central Uganda, uptake of optimal doses of IPTp-SP is very low. Improving institutional delivery
and household wealth, involving religious leaders in programmes to improve uptake of IPTp-SP, and strengthening
IPTp-SP activities at lower level health centers may improve uptake of IPTp-SP in the East-Central Uganda.
Description
Keywords
Intermittent preventive treatment during pregnancy, Malaria, Uganda, Demographic and health survey
Citation
Martin, M. K., Venantius, K. B., Patricia, N., Bernard, K., Keith, B., Allen, K., ... & Dathan, B. M. (2020). Correlates of uptake of optimal doses of sulfadoxine-pyrimethamine for prevention of malaria during pregnancy in East-Central Uganda. Malaria Journal, 19(1), 1-14. https://doi.org/10.1186/s12936-020-03230-8