Cross-Sectional Serological Survey for Leptospira spp. in Beef and Dairy Cattle in Two Districts in Uganda
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Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
International journal of environmental research and public health
Abstract
Seroprevalence of Leptospira spp. in cattle is unknown in Uganda. The aim of this study was
to estimate the seroprevalence of L. interrogans Icterohaemorrhagiae, Pomona, L. kirschneri Butembo,
Grippotyphosa, L. borgpetersenii Nigeria, Hardjo, Wolfii, and Kenya and an overall seroprevalence in
cattle from Kole and Mbale districts. Two hundred-seventy five bovine sera from 130 small holder
farms from Kole (n = 159) and Mbale (n = 116), collected between January and July 2015, were tested
for antibodies against eight Leptospira strains by Microscopic Agglutination Test. A titer of 100 was
considered seropositive, indicating past exposure. Overall, the seroprevalence was 19.27% (95% CI
14.9–24.5%). Pomona seroprevalence was highest with 9.45% (6.4–13.7%), followed by Kenya 5.09%
(2.9–8.6%), Nigeria 4.00% (2.1–7.2%),Wolfii 3.27% (1.6–6.3%), Butembo 1.86% (0.7–4.4%), Hardjo 1.45%
(0.5–3.9%), and Icterohaemorragiae and Grippotyphosa with less than 1% positive. Seroprevalence
did not differ between districts and gender (p 0.05). Seven animals had titers 400. Cross-reactions
or exposure to 1 serovar was measured in 43% of serum samples. Seroprevalence of 19% implies
exposure of cattle to leptospires.
Description
Keywords
Leptospirosis, Microscopic Agglutination Test, Uganda, Cattle, Seroprevalence
Citation
Dreyfus, A., Odoch, T., Alinaitwe, L., Rodriguez-Campos, S., Tsegay, A., Jaquier, V., & Kankya, C. (2017). Cross-Sectional serological survey for leptospira spp. In beef and dairy cattle in two districts in Uganda. International journal of environmental research and public health, 14(11), 1421. doi:10.3390/ijerph14111421