Virologic suppression and associated factors in HIV infected Ugandan female sex workers: a cross-sectional study

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dc.contributor.authorOwachi, Darius
dc.contributor.authorAnguzu, Godwin
dc.contributor.authorKigozi, Joanita
dc.contributor.authorCox, Janneke
dc.contributor.authorCastelnuovo, Barbara
dc.contributor.authorSemitala, Fred
dc.contributor.authorMeya, David
dc.date.accessioned2023-06-01T19:00:11Z
dc.date.available2023-06-01T19:00:11Z
dc.date.issued2021
dc.description.abstractKey populations have disproportionately higher HIV prevalence rates than the general population. To determine the level of virologic suppression and associated factors in female Commercial Sex Workers (CSW) who completed six months of ART and compare with the female general population (GP). Clinical records of CSW and GPs who initiated ART between December 2014 to December 2016 from seven urban clinics were analyzed to determine virologic suppression (viral load < 1000 copies/ml) and associated factors. We identified 218 CSW and 182 female GPs. CSW had median age of 28 (IQR 25-31) vs 31 (IQR 26-37); median baseline CD4 446 (IQR 308-696) vs 352 (IQR 164–493) cells/microL; and optimal ART adherence levels at 70.6% vs 92.8% respectively, compared to GP. Virologic suppression in CSW and GPs was 85.7% and 89.6% respectively, P=0.28. Overall virologic suppression in CSW was 55% while Retention in care after 6 months of ART was 77.5%. Immediate ART initiation (<2weeks) and tuberculosis independently predicted virologic suppression in CSW with adjusted odds ratios 0.07 (95% C.I. 0.01-0.55, P=0.01) and 0.09 (95% C.I. 0.01-0.96, P=0.046) respectively. Virologic suppression in both groups is similar, however, intensified follow-up is needed to improve treatment outcomes.en_US
dc.identifier.citationOwachi, D., Anguzu, G., Kigozi, J., Cox, J., Castelnuovo, B., Semitala, F., & Meya, D. (2021). Virologic suppression and associated factors in HIV infected Ugandan female sex workers: a cross-sectional study. African Health Sciences, 21(2), 603-613.https://doi.org/10.4314/ahs.v21i2.15en_US
dc.identifier.issn1729-0503
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8868
dc.language.isoenen_US
dc.publisherAfrican Health Sciencesen_US
dc.subjectHIV infected Ugandansen_US
dc.subjectFemale sex workersen_US
dc.titleVirologic suppression and associated factors in HIV infected Ugandan female sex workers: a cross-sectional studyen_US
dc.typeArticleen_US
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