Analysis of Host Responses to Mycobacterium tuberculosis Antigens in a Multi-Site Study of Subjects with Different TB and HIV Infection States in Sub-Saharan Africa

Abstract
Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to define the antigens expressed by Mycobacterium tuberculosis (Mtb), which are relevant to protective immunity in high-endemic areas.
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Citation
Sutherland, J. S., Lalor, M. K., Black, G. F., Ambrose, L. R., Loxton, A. G., Chegou, N. N., ... & GCGH Biomarkers for TB consortium. (2013). Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. PloS one, 8(9), e74080.doi:10.1371/journal.pone. 0074080