Occurrence of Foot-and-Mouth Disease Virus Serotypes in Uganda and Tanzania (2003 to 2015): A Review and Implications for Prospective Regional Disease Control
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Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
Journal of Agricultural Science
Abstract
Endemic foot-and-mouth disease (FMD) presents a global economic challenge to the livestock industry. The
progressive control pathway for FMD (PCP-FMD) specifies successive steps through which a country/region can
reduce FMD virus circulation and impact. These steps are reliant on understanding and obtaining knowledge on
FMD epidemiology, to inform development of appropriate disease interventions like vaccination and quarantine
programs. Currently, Uganda and Tanzania are in the early stages of the PCP-FMD.
This review was undertaken to determine FMDV serotype distribution in Uganda and Tanzania between 2003
and 2015. The paper also presents the vaccine strains used in both countries for the same period viz avis the
circulating topotypes. The review highlights four (O, A, SAT 1 and SAT 2) and five (O, A, SAT 1, SAT 2 and
SAT 3) serotypes that occurred in Uganda and Tanzania respectively in the thirteen year period. Observations
revealed that reported circulating serotypes O and A in the two countries belonged to similar topotypes, East
African 2 (EA-2) and AFRICA respectively. The SAT 1 viruses in Tanzania belonged to topotype I and differed
from the Ugandan SAT 1s that belonged to topotype IV. Similarly, the SAT 2s in both countries belonged to
different topotypes: IV in Tanzania and I in Uganda. This review additionally, underscores the spatial distribution
of FMDV serotypes in Uganda and Tanzania and highlights regions in both countries that had high serotype
diversity.
The paper recommends definitive disease diagnoses, molecular serotype characterisation and matched
vaccination deployment for improved disease control.
Description
Keywords
Control, Epidemiology, Foot-and-mouth disease, Serotypes
Citation
Kerfua, S., Dhikusooka, M., Mulondo, A., Bugeza, J., Kabi, F., Shirima, G., ... & Haydon, D. (2020). Occurrence of Foot-and-Mouth Disease Virus Serotypes in Uganda and Tanzania (2003 to 2015): A Review and Implications for Prospective Regional Disease Control. https://doi.org/10.5539/jas.v12n6p119