Expanded Phase I safety and acceptability study of 6% cellulose sulfate vaginal gel
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Date
2005
Journal Title
Journal ISSN
Volume Title
Publisher
AIDS
Abstract
An expanded Phase I trial was performed to assess the safety and acceptability of 6% cellulose sulfate gel (CS) in comparison with K-Y Jelly.
Sexually abstinent (cohort I) and sexually active (cohort II) women in India, Nigeria and Uganda applied 3.5 ml of either 6% CS gel or K-Y Jelly for seven consecutive days. Safety was assessed by symptoms and signs (including colposcopy) of genital irritation, review of adverse events, and by changes in vaginal health as assessed by microscopy.
Description
Keywords
Cellulose sulphate, Microbicide, Vaginal gel, HIV prevention, Sexually transmitted infections, Phase I clinical trial
Citation
Malonza, I. M., Mirembe, F., Nakabiito, C., Odusoga, L. O., Osinupebi, O. A., Hazari, K., ... & Van Damme, L. (2005). Expanded Phase I safety and acceptability study of 6% cellulose sulfate vaginal gel. Aids, 19(18), 2157-2163.