Antibiotic Prevalence Study and Factors Influencing Prescription of WHO Watch Category Antibiotic Ceftriaxone in a Tertiary Care Private Not for Profit Hospital in Uganda

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dc.contributor.authorKizito, Mark
dc.contributor.authorLalitha, Rejani
dc.contributor.authorKajumbula, Henry
dc.contributor.authorSsenyonga, Ronald
dc.contributor.authorMuyanja, David
dc.contributor.authorByakika-Kibwika, Pauline
dc.date.accessioned2022-01-12T08:12:27Z
dc.date.available2022-01-12T08:12:27Z
dc.date.issued2021
dc.description.abstractExcessive use of ceftriaxone contributes to the emergence and spread of antimicrobial resistance (AMR). In low and middle-income countries, antibiotics are overused but data on consumption are scarcely available. We aimed to determine the prevalence and factors influencing ceftriaxone prescription in a tertiary care private not-for-profit hospital in Uganda. Methods: A cross-sectional study was carried out from October 2019 through May 2020 at Mengo Hospital in Uganda. Patients admitted to the medical ward and who had been prescribed antibiotics were enrolled. Sociodemographic and clinical data were recorded in a structured questionnaire. Bivariate and adjusted logistic regression analyses were performed to determine factors associated with ceftriaxone prescription. Results: Study participants were mostly female (54.7%). The mean age was 56.2 years (SD: 21.42). The majority (187, 73.3%) presented with fever. Out of the 255 participants included in this study, 129 (50.6%) participants were prescribed ceftriaxone. Sixty-five (25.5%) and forty-one (16.0%) participants had a prescription of levofloxacin and metronidazole, respectively. Seven participants (2.7%) had a prescription of meropenem. Out of 129 ceftriaxone prescriptions, 31 (24.0%) were in combination with other antibiotics. Overall, broad-spectrum antibiotic prescriptions accounted for 216 (84.7%) of all prescriptionsen_US
dc.identifier.citationKizito, M.; Lalitha, R.; Kajumbula, H.; Ssenyonga, R.; Muyanja, D.; Byakika-Kibwika, P. Antibiotic Prevalence Study and Factors Influencing Prescription of WHO Watch Category Antibiotic Ceftriaxone in a Tertiary Care Private Not for Profit Hospital in Uganda. Antibiotics 2021, 10, 1167. https:// doi.org/10.3390/antibiotics10101167en_US
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1201
dc.language.isoenen_US
dc.publisherAntibioticsen_US
dc.subjectCeftriaxone prescriptionen_US
dc.subjectPrevalenceen_US
dc.subjectAntibiotic stewardshipen_US
dc.subjectUgandaen_US
dc.titleAntibiotic Prevalence Study and Factors Influencing Prescription of WHO Watch Category Antibiotic Ceftriaxone in a Tertiary Care Private Not for Profit Hospital in Ugandaen_US
dc.typeArticleen_US
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