Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease

Rheumatic heart disease affects more than 40.5 million people worldwide and results in 306,000 deaths annually. Echocardiographic screening detects rheumatic heart disease at an early, latent stage. Whether secondary antibiotic prophylaxis is effective in preventing progression of latent rheumatic heart disease is unknown.
Latent Rheumatic Heart Disease, Antibiotic Prophylaxis
Beaton, A., Okello, E., Rwebembera, J., Grobler, A., Engelman, D., Alepere, J., ... & Steer, A. C. (2022). Secondary antibiotic prophylaxis for latent rheumatic heart disease. New England Journal of Medicine, 386(3), 230-240.DOI: 10.1056/NEJMoa2102074