Prevalence of and characteristics associated with in-hospital mortality in a Ugandan neurology ward
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Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
BMC neurology
Abstract
While the burden of neurologic illness in developing countries is increasing, less is known about mortality among patients admitted to sub-Saharan African hospitals with neurologic disease. We sought to characterize the rate and patient-level predictors of in-hospital mortality in a Ugandan Neurology ward.cc.
Data was prospectively collected on 335 patients admitted to the Neurology ward of Mulago Hospital, Kampala, Uganda. Kaplan-Meier survival curves and multivariate COX proportional hazard modeling were used to assess survival.
Within our sample (n = 307), 35.8% received no diagnosis at time of hospital admission. Stroke (27.3%), head trauma (19.6%), and malaria (16.0%) were the most common diagnoses. Among the 56 (18.5%) patients who died during the index hospitalization, the most common diagnosis at admission and at death was stroke. Adjusted regression analysis showed that patients without a diagnosis at time of death (HR = 7.01 [2.42–20.35], p < .001) and those with diagnoses of infections (HR = 5.21 [2.16–12.58], p = <.001), stroke (HR = 2.69 [1.20–6.04], p = .017), or head trauma (HR = 3.39, [1.27–9.07], p = 0.15) had worse survival.
Description
Keywords
Uganda, Neurological illness, Neurological infections, Stroke, Head trauma, Global neurology
Citation
Diaz, M. M., Hu, X., Fenton, B. T., Kimuli, I., Lee, A., Lindsey, H., ... & Sico, J. J. (2020). Prevalence of and characteristics associated with in-hospital mortality in a Ugandan neurology ward. BMC neurology, 20(1), 1-13. https://doi.org/10.1186/s12883-020-1627-5