Urban and rural prevalence of diabetes and prediabetes and risk factors associated with diabetes in Tanzania and Uganda

dc.contributor.authorChiwanga, Faraja S.
dc.contributor.authorNjelekela, Marina A.
dc.contributor.authorDiamond, Megan B.
dc.contributor.authorBajunirwe, Francis
dc.contributor.authorGuwatudde, David
dc.contributor.authorNankya-Mutyoba, Joan
dc.contributor.authorKalyesubula, Robert
dc.contributor.authorAdebamowo, Clement
dc.contributor.authorAjayi, IkeOluwapo
dc.contributor.authorReid, Todd G.
dc.contributor.authorVolmink, Jimmy
dc.contributor.authorLaurence, Carien
dc.contributor.authorDalal, Shona
dc.date.accessioned2022-04-30T10:50:49Z
dc.date.available2022-04-30T10:50:49Z
dc.date.issued2016
dc.description.abstractThe increase in prevalence of diabetes and pre-diabetes in sub-Saharan Africa underlines the importance of understanding its magnitude and causes in different population groups. We analyzed data from the Africa/Harvard Partnership for Cohort Research and Training (PaCT) studies to determine the prevalence of diabetes and pre-diabetes and risk factors associated with diabetes. Methodology: Participants were randomly selected from peri-urban (n 297) and rural (n 200) communities in Uganda, and teachers were recruited from schools (n 229) in urban Tanzania. We used a standardized questionnaire to collect socio-demographic and self-reported disease status including diabetes status. Blood glucose was also measured after participants fasted for 8 h. We used standard protocols for anthropometric and blood pressure measurement. Results: The overall prevalence of diabetes was 10.1% and was highest in rural Ugandan residents (16.1%) compared to teachers in Tanzania (8.3%) and peri-urban Ugandan residents (7.6%). The prevalence of prediabetes was 13.8%. The prevalence of self-reported diabetes was low across all sites, where 68% of participants with diabetes were not captured by self-report. In multivariable logistic regression analysis, family history (OR 2.5, 95% CI: 1.1, 5.6) and hypertension (OR 2.3, 95% CI: 1.1, 5.2) were significantly associated with diabetes. Conclusions: The prevalence of diabetes and pre-diabetes in Uganda and Tanzania is high, differs markedly between population groups, and remains undiagnosed in an alarmingly high proportion of individuals. These findings highlight the need for large-scale, prospective studies to accurately quantify the burden and identify effective intervention and treatment strategies across diverse African populations.en_US
dc.identifier.citationFaraja S. Chiwanga, Marina A. Njelekela, Megan B. Diamond, Francis Bajunirwe, David Guwatudde, Joan Nankya-Mutyoba, Robert Kalyesubula, Clement Adebamowo, IkeOluwapo Ajayi, Todd G. Reid, Jimmy Volmink, Carien Laurence, Hans-Olov Adami, Michelle D. Holmes & Shona Dalal (2016) Urban and rural prevalence of diabetes and pre-diabetes and risk factors associated with diabetes in Tanzania and Uganda, Global Health Action, 9:1, 31440, DOI: 10.3402/gha.v9.31440en_US
dc.identifier.other10.3402/gha.v9.31440
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/3046
dc.language.isoenen_US
dc.publisherGlobal Health Actionen_US
dc.subjectNon-communicableen_US
dc.subjectRisk factorsen_US
dc.subjectUnderdiagnosesen_US
dc.subjectSub-Saharan Africaen_US
dc.subjectTanzaniaen_US
dc.subjectUgandaen_US
dc.titleUrban and rural prevalence of diabetes and prediabetes and risk factors associated with diabetes in Tanzania and Ugandaen_US
dc.typeArticleen_US
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