Antimicrobial activity and phytochemical fingerprints of five crude extracts obtained from indigenous medicinal plants of Uganda

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dc.contributor.authorKatuura, Esther
dc.contributor.authorBossa, Godfrey Sande
dc.contributor.authorWaako, Paul
dc.contributor.authorOgwal -Okeng, Jasper
dc.date.accessioned2021-12-14T11:39:47Z
dc.date.available2021-12-14T11:39:47Z
dc.date.issued2017
dc.description.abstractFive crude extracts from four Ugandan plants were screened in vitro for their antimicrobial activity and phytochemical composition. They included the chloroform extracts of Bothliocline longipes, Maesa lanceolata, Trimeria bakeri, Rhus natalensis and the petroleum ether extract of T. bakeri. The plant crude extracts were tested against Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 49619) and Entamoeba sp. Antimicrobial activities of the plants were determined by using the agar well diffusion and agar well dilution methods. The plant extracts showed activity against all the tested organisms with the zones of inhibition ranging from 4 to 19 mm. All the extracts inhibited the growth of S. aureus while the strongest activity was found for T. bakeri against S. aureus and Entamoeba sp. at 19 mm. Other plant extracts that induced strong antimicrobial activity were the chloroform extract of R. natalensis with an inhibition diameter of 13 mm against both S. aureas and P. aeruginosa and 9 mm diameter inhibition against E. coli. Only T. bakeri showed growth inhibition of S. aureus (4 mm). The minimum inhibitory concentration (MIC) was observed against S. aureus at 0.25 g/ml by the T. bakeri and B. longipes plant extracts. Sterol and triterpenes, fatty acids, flavanoids, coumarins and alkaloids were determined in T. bakeri, B. longipes, R. natalensis and M. lanceolata. The presence of these compounds indicates that the plants may contain an active compound or one that can be used as a template for the development of a new antimalarial or antibiotic medicineen_US
dc.identifier.citationKatuura, E., Bbosa, G. S., Waako, P., & Ogwal-Okeng, J. (2017). Antimicrobial activity and phytochemical fingerprints of five crude extracts obtained from indigenous medicinal plants of Uganda.DOI: 10.5897/RPB2016.0104en_US
dc.identifier.issn2141-2324
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/489
dc.language.isoenen_US
dc.subjectAntimicrobialen_US
dc.subjectMedicinal plantsxen_US
dc.subjectMedicinal plantsen_US
dc.subjectFingerprintingen_US
dc.subjectPhytochemistry.en_US
dc.titleAntimicrobial activity and phytochemical fingerprints of five crude extracts obtained from indigenous medicinal plants of Ugandaen_US
dc.typeArticleen_US
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