Complex population structure in African village dogs and its implications for inferring dog domestication history
Loading...
Date
2009
Journal Title
Journal ISSN
Volume Title
Publisher
National Academy of Sciences
Abstract
High genetic diversity of East Asian village dogs has recently been
used to argue for an East Asian origin of the domestic dog. However,
global village dog genetic diversity and the extent to which semiferal
village dogs represent distinct, indigenous populations instead of
admixtures of various dog breeds has not been quantified. Understanding
these issues is critical to properly reconstructing the timing,
number, and locations of dog domestication. To address these questions,
we sampled 318 village dogs from 7 regions in Egypt, Uganda,
and Namibia, measuring genetic diversity >680 bp of the mitochondrial
D-loop, 300 SNPs, and 89 microsatellite markers. We also analyzed
breed dogs, including putatively African breeds (Afghan
hounds, Basenjis, Pharaoh hounds, Rhodesian ridgebacks, and Salukis),
Puerto Rican street dogs, and mixed breed dogs from the
United States. Village dogs from most African regions appear genetically
distinct from non-native breed and mixed-breed dogs, although
some individuals cluster genetically with Puerto Rican dogs or United
States breed mixes instead of with neighboring village dogs. Thus,
African village dogs are a mosaic of indigenous dogs descended from
early migrants to Africa, and non-native, breed-admixed individuals.
Among putatively African breeds, Pharaoh hounds, and Rhodesian
ridgebacks clustered with non-native rather than indigenous African
dogs, suggesting they have predominantly non-African origins. Surprisingly,
we find similar mtDNA haplotype diversity in African and
East Asian village dogs, potentially calling into question the hypothesis
of an East Asian origin for dog domestication.
Description
Keywords
Microsatellites, Principal component analysis, Single nucleotide polymorphisms
Citation
Boyko, A. R., Boyko, R. H., Boyko, C. M., Parker, H. G., Castelhano, M., Corey, L., ... & Bustamante, C. D. (2009). Complex population structure in African village dogs and its implications for inferring dog domestication history. Proceedings of the National Academy of Sciences, 106(33), 13903-13908. doi/10.1073/pnas.0902129106