A Cluster-Randomised Trial to Compare Home-Based with Health Facility- Based Antiretroviral Treatment in Uganda: Study Design and Baseline Findings

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dc.contributor.authorAmuron, Barbara
dc.contributor.authorCoutinho, Alex
dc.contributor.authorGrosskurth, Heiner
dc.contributor.authorNabiryo, Christine
dc.contributor.authorBirungi, Josephine
dc.contributor.authorNamara, Geoffrey
dc.contributor.authorLevin, Jonathan
dc.contributor.authorSmith, Peter G.
dc.contributor.authorJaffar, Shabbar
dc.date.accessioned2021-12-15T12:40:11Z
dc.date.available2021-12-15T12:40:11Z
dc.date.issued2007
dc.description.abstractThe scale-up of antiretroviral therapy is progressing rapidly in Africa but with a limited evidence-base. We re- port the baseline results from a large pragmatic cluster-randomised trial comparing different strategies of ART delivery. The trial is integrated in normal health service delivery. 1453 subjects were recruited into the study. Significantly more women (71%) than men (29%) were recruited. The WHO HIV clinical stage at presentation did not differ significantly between men and women: 58% and 53% respectively were at WHO stage III or IV (p=0.9). Median CD4 counts (IQR) x 10 6 cells/l were 98 (28, 160) among men and 111 (36, 166) among women. Sixty-four percent of women and 61% men had plasma viral load 100,000 copies. Baseline characteris- tics did not change over time. Considerably fewer men than women presented for treatment.en_US
dc.identifier.citationAmuron, B., Coutinho, A., Grosskurth, H., Nabiryo, C., Birungi,J., Namara., G., Smith. P.G., Smith, S. (2007). A Cluster-Randomised Trial to Compare Home-Based with Health Facility- Based Antiretroviral Treatment in Uganda: Study Design and Baseline Findings. Bentham Science Publishers Ltd: The Open AIDS Journal, 1, 21-27en_US
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/613
dc.language.isoenen_US
dc.publisherBentham Science Publishers Ltd.en_US
dc.subjectCluster-randomised trialen_US
dc.subjectAnti-retroviral therapyen_US
dc.subjectEffectiveness trialen_US
dc.subjectAfricaen_US
dc.subjectHome-based HIV careen_US
dc.subjectBaseline characteristicsen_US
dc.subjectEquityen_US
dc.titleA Cluster-Randomised Trial to Compare Home-Based with Health Facility- Based Antiretroviral Treatment in Uganda: Study Design and Baseline Findingsen_US
dc.typeArticleen_US
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