Circumcision as an Intervening Strategy against HIV Acquisition in the Male Genital Tract

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dc.contributor.authorLakhikumar Sharma, Adhikarimayum
dc.contributor.authorHokello, Joseph
dc.contributor.authorTyagi, Mudit
dc.date.accessioned2022-12-05T13:42:27Z
dc.date.available2022-12-05T13:42:27Z
dc.date.issued2021
dc.description.abstractUnsafe sex with HIV-infected individuals remains a major route for HIV transmission, and protective strategies, such as the distribution of free condoms and pre-or post-prophylaxis medication, have failed to control the spread of HIV, particularly in resource-limited settings and high HIV prevalence areas. An additional key strategy for HIV prevention is voluntary male circumcision (MC). International health organizations (e.g., the World Health Organization, UNAIDS) have recommended this strategy on a larger scale, however, there is a general lack of public understanding about how MC effectively protects against HIV infection. This review aims to discuss the acquisition of HIV through the male genital tract and explain how and why circumcised men are more protected from HIV infection during sexual activity than uncircumcised men who are at higher risk of HIV acquisition.en_US
dc.identifier.citationSharma, A.L.; Hokello, J.; Tyagi, M. Circumcision as an Intervening Strategy against HIV Acquisition in the Male Genital Tract. Pathogens 2021, 10, 806. https:// doi.org/10.3390/pathogens10070806en_US
dc.identifier.urihttps:// doi.org/10.3390/pathogens10070806
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/5888
dc.language.isoenen_US
dc.publisherPathogensen_US
dc.subjectHIVen_US
dc.subjectviral transmissionen_US
dc.subjectcircumcisionen_US
dc.subjectheterosexual HIV-1 transmissionen_US
dc.titleCircumcision as an Intervening Strategy against HIV Acquisition in the Male Genital Tracten_US
dc.typeArticleen_US
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