Pre-vaccination Schistosoma mansoni and hookworm infections are associated with altered vaccine immune responses: a longitudinal analysis among adolescents living in helminth-endemic islands of Lake Victoria, Uganda

dc.contributor.authorNatukunda, Agnes
dc.contributor.authorZirimenya,Ludoviko
dc.contributor.authorNkurunungi, Gyaviira
dc.contributor.authorNassuuna, Jacent
dc.date.accessioned2025-06-24T09:13:18Z
dc.date.available2025-06-24T09:13:18Z
dc.date.issued2024-08-29
dc.description.abstractVariations in vaccine responses have been observed between populations. A role for helminth infections has been proposed due to their immunomodulatory properties. In a secondary analysis of data from a randomised trial assessing effects of anthelminthic treatment on vaccine responses, we examined associations between helminth infections at baseline prior to vaccine administration, and vaccine responses among adolescents (9-17 years) in Koome Islands, Lake Victoria, Uganda.
dc.identifier.citationNatukunda, A., Zirimenya, L., Nkurunungi, G., Nassuuna, J., Nkangi, R., Mutebe, A., ... & Webb, E. L. (2024). Pre-vaccination Schistosoma mansoni and hookworm infections are associated with altered vaccine immune responses: a longitudinal analysis among adolescents living in helminth-endemic islands of Lake Victoria, Uganda. Frontiers in Immunology, 15, 1460183.
dc.identifier.otherhttps://doi.org/10.3389/fimmu.2024.1460183
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/11892
dc.language.isoen
dc.publisherFrontiers in Immunology
dc.titlePre-vaccination Schistosoma mansoni and hookworm infections are associated with altered vaccine immune responses: a longitudinal analysis among adolescents living in helminth-endemic islands of Lake Victoria, Uganda
dc.typeArticle
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