Sero-prevalence of Herpes Simplex Type 2 Virus (HSV-2) and HIV Infection in Kampala, Uganda

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dc.contributor.authorNakku-Joloba, Edith
dc.contributor.authorKambugu, Fred
dc.contributor.authorWasubire, Julius
dc.contributor.authorKimeze, Joshua
dc.contributor.authorSalata, Robert
dc.contributor.authorAlbert, Jeffrey M.
dc.contributor.authorRimm, Alfred
dc.contributor.authorWhalen, Christopher
dc.date.accessioned2022-04-05T19:33:39Z
dc.date.available2022-04-05T19:33:39Z
dc.date.issued2014
dc.description.abstractPrevalence of herpes simplex type 2 virus (HSV-2) is high worldwide. Previous studies in Uganda were rural or in women. We estimated age and sex-specific sero- prevalence of HSV-2 in Kampala, Uganda.Using two-stage random sampling stratified on population density, a survey of persons 15-65 years was conducted. Type-specific serological tests for HSV-2, HSV-1(HerpeSelect2 and 1 ELISA), HIV (Rapid tests and ELISA), syphilis (RPR and TPHA) were done. Additional prevalence analysis included post-stratification weighting on the Uganda 2002 Census gender distribution.Among 1124 persons, HSV-2 prevalence was 58% (95% CI: 55, 60), HSV-1; 98% (95% CI: 97.6, 99.1), HIV; 17.7% (95% CI: 14.8, 19.2) and syphilis; 1.7% (95% CI: 1.4, 1.9). Weighted HSV-2 prevalence was 53.8% (Women; 63.8%, men; 43.2%), similar to unweighted data. Weighted HIV prevalence was 20.7% in women, 8.6% in men. Of 165 HIV infected persons, 85.4% had HSV-2. Risk factors for HSV-2 were being a woman (OR 2.0; 95% CI: 1.42, 2.78), age (OR 3.3; 95% CI: 2.43, 4.53), education (OR 1.70; 95% CI: 1.34, 2.34) and HIV (OR 4.5; 95% CI: 2.70, 7.50).Prevalence of HSV-2 and HIV was high especially in women. Syphilis was rare. Awareness of herpes was low. Interventions in young people are needed.en_US
dc.identifier.citationNakku-Joloba, E., Kambugu, F., Wasubire, J., Kimeze, J., Salata, R., Albert, J. M., ... & Whalen, C. (2014). Sero-prevalence of herpes simplex type 2 virus (HSV-2) and HIV infection in Kampala, Uganda. African health sciences, 14(4), 782-789.https://doi.org/10.4314/ahs.v14i4.2en_US
dc.identifier.issn1680-6905
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/2891
dc.language.isoenen_US
dc.publisherAfrican health sciencesen_US
dc.subjectHSV-2, HIV, Kampala Ugandaen_US
dc.titleSero-prevalence of Herpes Simplex Type 2 Virus (HSV-2) and HIV Infection in Kampala, Ugandaen_US
dc.typeArticleen_US
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