Diagnostic accuracy of fine needle aspiration cytology in patients undergoing thyroidectomy in Uganda: tertiary hospital experience.

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dc.contributor.authorMasereka, Robert
dc.contributor.authorOkeny, Paul K.
dc.contributor.authorFualal, Jane .O.
dc.contributor.authorWamala, Dan
dc.date.accessioned2023-03-20T09:17:19Z
dc.date.available2023-03-20T09:17:19Z
dc.date.issued2016
dc.description.abstractThyroid disease affects about 5% of the World’s population. Fine Needle Aspiration Cytology (FNAC) helps in planning extent of surgery. In some studies, FNAC has been found to have a low accuracy for malignancy. To estimate the sensitivity and specificity of FNAC in detecting malignancy for thyroid disease using histopathology as the gold standard. Patients who underwent clinical and laboratory evaluation and thyroidectomy at Mulago National Referral hospital and the Pathology department of Makerere University College of Health Sciences were consecutively recruited over a four months period. Analysis using STATA version 10 focused on sensitivity, specificity and accuracy of FNAC in detecting malignancy. In total, 99 patients were recruited, the F:M ratio was 15.5:1 and median age was 42 years (IQR 34-50). The median duration of symptoms was 364 weeks (IQR 104-986). The proportion of patients with malignancy was 13.3% with papillary thyroid carcinoma being the most predominant type and colloid goiter was the most predominant benign thyroid disease. The sensitivity was 61.5% and specificity 89.5% . This study revealed high specificity and low sensitivity of Fine Needle Aspiration Cytology (FNAC) at detecting malignancy in thyroid nodulesen_US
dc.identifier.citationMasereka, R., Okeny, P. K., Fualal, J. O., & Wamala, D. (2016). Diagnostic accuracy of fine needle aspiration cytology in patients undergoing thyroidectomy in Uganda: tertiary hospital experience. African health sciences, 16(4), 1143-1150.https://doi.org/10.4314/ahs.v16i4.32en_US
dc.identifier.issn1729-0503
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8240
dc.language.isoenen_US
dc.publisherAfrican health sciencesen_US
dc.subjectDiagnostic accuracyen_US
dc.subjectFine needle aspirationen_US
dc.subjectCytologyen_US
dc.titleDiagnostic accuracy of fine needle aspiration cytology in patients undergoing thyroidectomy in Uganda: tertiary hospital experience.en_US
dc.typeArticleen_US
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