A case of toxoplasmic encephalitis in a patient on cancer chemotherapy in Uganda

Simple item page
dc.contributor.authorMitala, Yekosani
dc.contributor.authorAtwine, Raymond
dc.contributor.authorBirungi, Abraham
dc.contributor.authorAmbaru, Jacinta
dc.contributor.authorKuraishi, Baluku
dc.contributor.authorSekitene, Semei
dc.contributor.authorNuwagira, Edwin
dc.date.accessioned2025-05-03T12:21:17Z
dc.date.available2025-05-03T12:21:17Z
dc.date.issued2025-01-11
dc.description.abstractBackground: Reactivation of central nervous system (CNS) toxoplasmosis can be caused by immunosuppression (ISS) of any kind. However, anti-cancer chemotherapy combined with human immunodeficiency virus (HIV) induced ISS results in an atypical presentation that is fatal. Case presentation: A 46 years old man with a well-controlled infection of the human immunodeficiency virus presented with generalized tonic-clonic seizures following the second dose of anti-cancer chemotherapy for esophageal cancer. His brain's computerized tomography (CT) scan showed enlarged ventricles with no space-occupying lesions. Cerebrospinal fluid (CSF) smears stained with hematoxylin and eosin (H&E) revealed numerous bradyzoites and tachyzoites consistent with central nervous system toxoplasmosis. Conclusion: With a double burden of cancer and Human immunodeficiency virus (HIV) infection in low-income countries, this case raises awareness about the atypical presentation of CNS toxoplasmosis reactivation among patients on cancer chemotherapy.
dc.identifier.citationMitala Y, Atwine R, Birungi A, Jacinta A, Baluku K, Sekitene S, et al. A case of toxoplasmic encephalitis in a patient on cancer chemotherapy in Uganda. Afri Health Sci. 2024; 24(4). 106-110. https://dx.doi.org/10.4314/ahs.v24i4.14
dc.identifier.doi10.4314/ahs.v24i4.14
dc.identifier.issn1729-0503
dc.identifier.issn1680-6905
dc.identifier.urihttps://dx.doi.org/10.4314/ahs.v24i4.14
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/11368
dc.language.isoen
dc.publisherAfrican Journals Online (AJOL)
dc.relation.ispartofAfrican Health Sciences
dc.titleA case of toxoplasmic encephalitis in a patient on cancer chemotherapy in Uganda
dc.typejournal-article
oaire.citation.issue4
oaire.citation.volume24
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ajol-file-journals_45_articles_286061_678103b30c40e.pdf
Size:
320.47 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medical and Health Sciences