Few Losses to Follow-up in a Sub-Saharan African Cancer Cohort via Active Mobile Health Follow-up

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dc.contributor.authorFoerster, Milena
dc.contributor.authorAnele, Angelica
dc.contributor.authorAdisa, Charles
dc.contributor.authorGalukande, Moses
dc.contributor.authorOyamienlen, Christopher Sule
dc.contributor.authorBakengesa, Evelyn
dc.contributor.authorKaggwa, Agnes
dc.contributor.authorNaamala, Allen
dc.contributor.authorNteziryayo, Anne
dc.contributor.authorNakazibwe, Teopista
dc.contributor.authorWalubita, Emily
dc.contributor.authorAnderson, Benjamin O.
dc.contributor.authorSilva, Isabel dos Santos
dc.contributor.authorMcCormack, Valerie
dc.date.accessioned2023-03-27T09:41:55Z
dc.date.available2023-03-27T09:41:55Z
dc.date.issued2020
dc.description.abstractAccurate survival estimates are needed for guiding cancer control efforts in sub-Saharan Africa, but previous studies have been hampered by unknown biases due to excessive loss to follow-up (LTFU). In the African Breast Cancer—Disparities in Outcomes Study, a prospective breast cancer cohort study, we implemented active mobile health follow-up, telephoning each woman or her next-of-kin (NOK) trimonthly on her mobile phone to update information on her vital status. Dates of every contact with women/NOK were analyzed from diagnosis in 2014–2017 to the earliest of September 1, 2018, death, or 3 years postdiagnosis. The cumulative incidence of being LTFU was calculated considering deaths as competing events. In all, 1,490 women were followed for a median of 24.2 (interquartile range (IQR), 14.2–34.5) months, corresponding to 8,529 successful contacts (77% of total contacts) with the women/NOK. Median time between successful contacts was 3.0 (IQR, 3.0–3.7) months. In all, 71 women (5.3%) were LTFU at 3 years: 0.8% in Nigeria, 2.2% in Namibia, and 5.6% in Uganda. Because of temporary discontinuity of active follow-up, 20.3% of women were LTFU after 2 years in Zambia. The median time to study notification of a death was 9.1 (IQR, 3.9–14.0) weeks. Although the present study was not a randomized controlled trial, in this cancer cohort with active mobile health follow-up, LTFU was much lower than in previous studies and enabled estimation of up-to-date and reliable cancer survival.en_US
dc.identifier.citationFoerster, M., Anele, A., Adisa, C., Galukande, M., Parham, G., Zietsman, A., ... & McCormack, V. (2020). Few Losses to Follow-up in a Sub-Saharan African Cancer Cohort via Active Mobile Health Follow-up: The African Breast Cancer—Disparities in Outcomes Study. American journal of epidemiology, 189(10), 1185-1196.https://doi.org/10.1093/aje/kwaa070en_US
dc.identifier.issn1476-6256
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8305
dc.language.isoenen_US
dc.publisherAmerican journal of epidemiologyen_US
dc.subjectBreast canceren_US
dc.subjectCancer survivalen_US
dc.subjectLoss to follow-upen_US
dc.subjectMobile healthen_US
dc.subjectProspective studiesen_US
dc.titleFew Losses to Follow-up in a Sub-Saharan African Cancer Cohort via Active Mobile Health Follow-upen_US
dc.typeArticleen_US
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