Hypertension Persisting after Pre-Eclampsia: A Prospective Cohort Study at Mulago Hospital, Uganda

Abstract
Pre-eclampsia/eclampsia usually resolves after delivery but sometimes hypertension persists and cardiovascular disease develops later. Our objective was to determine the incidence and maternal sociodemographic and obstetric risk factors for persistence of hypertension in women with pre-eclampsia/eclampsia. Methods: This was a prospective cohort study conducted from July 2009 to June 2011 at Mulago Hospital labour ward and postnatal clinics. We followed up 188 women admitted with pre-eclampsia/eclampsia until 3 months after delivery. Data was collected using interviewer-administered questionnaires, examination of participants and review of medical records. Stata (version12) software was used for data analysis. Univariable analysis was used to compute the relative risk of persistent hypertension at the 95% confidence level. This was followed by multivariable logistic regression analysis to determine factors independently associated with persistence of hypertension.
Description
Keywords
Hypertension, Pre-Eclampsia, Cohort Study, Mulago Hospital, Uganda
Citation
Nakimuli A, Elliott AM, Kaleebu P, Moffett A, Mirembe F (2013) Hypertension Persisting after Pre-Eclampsia: A Prospective Cohort Study at Mulago Hospital, Uganda . PLoS ONE 8(12): e85273. doi:10.1371/journal.pone.0085273