Antiretroviral Agents and Prevention of Malaria in HIV-Infected Ugandan Children

Abstract
Human immunodeficiency virus (HIV) protease inhibitors show activity against Plasmodium falciparum in vitro. We hypothesized that the incidence of malaria in HIV infected children would be lower among children receiving lopinavir–ritonavir– based antiretroviral therapy (ART) than among those receiving nonnucleosidereverse transcriptase inhibitor (NNRTI)–based ART.
Description
Keywords
Malaria, HIV-Infected, Children
Citation
Achan, J., Kakuru, A., Ikilezi, G., Ruel, T., Clark, T. D., Nsanzabana, C., ... & Kamya, M. R. (2012). Antiretroviral agents and prevention of malaria in HIV-infected Ugandan children. New England Journal of Medicine, 367(22), 2110-2118. DOI: 10.1056/NEJMoa1200501